BTF3 (basic transcription factor 3)

2007-10-01  

Identity

HGNC
LOCATION
5q13.2
LOCUSID
ALIAS
BETA-NAC,BTF3a,BTF3b,NACB
FUSION GENES

Other Information

Locus ID:

NCBI: 689
MIM: 602542
HGNC: 1125
Ensembl: ENSG00000145741

Variants:

dbSNP: 689
ClinVar: 689
TCGA: ENSG00000145741
COSMIC: BTF3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000145741ENST00000335895P20290
ENSG00000145741ENST00000380591P20290
ENSG00000145741ENST00000507081D6RDG3
ENSG00000145741ENST00000509708H0Y9Y1

Expression (GTEx)

0
500
1000
1500

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
23201281990Sequencing and expression of complementary DNA for the general transcription factor BTF3.39
243863642013Quantitative analysis of BTF3, HINT1, NDRG1 and ODC1 protein over-expression in human prostate cancer tissue.17
173123872007Basic transcription factor 3 (BTF3) regulates transcription of tumor-associated genes in pancreatic cancer cells.16
239012242013Basic transcription factor 3 is involved in gastric cancer development and progression.10
233639352013Fine-mapping of 5q12.1-13.3 unveils new genetic contributors to caries.9
235326892013Clinicopathological significance of BTF3 expression in colorectal cancer.8
180252622007Interaction between transcription factor, basal transcription factor 3, and the NH2-terminal domain of human estrogen receptor alpha.7
282763102017Basic Transcription Factor 3 Is Required for Proliferation and Epithelial-Mesenchymal Transition via Regulation of FOXM1 and JAK2/STAT3 Signaling in Gastric Cancer.6
303158452019Inhibition of BTF3 sensitizes luminal breast cancer cells to PI3Kα inhibition through the transcriptional regulation of ERα.5
311383112019BTF3 sustains cancer stem-like phenotype of prostate cancer via stabilization of BMI1.2

Citation

Dessen P

BTF3 (basic transcription factor 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-10-01

Online version: http://atlasgeneticsoncology.org/gene/49761/btf3-(basic-transcription-factor-3)