Identity
HGNC
LOCATION
9q31.1
LOCUSID
ALIAS
CAP-E,CAPE,SMC-2,SMC2L1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10592
MIM: 605576
HGNC: 14011
Ensembl: ENSG00000136824
Variants:
dbSNP: 10592
ClinVar: 10592
TCGA: ENSG00000136824
COSMIC: SMC2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38729325 | 2024 | SMC2 knockdown inhibits malignant progression of lung adenocarcinoma by upregulating BTG2 expression. | 0 |
| 38729325 | 2024 | SMC2 knockdown inhibits malignant progression of lung adenocarcinoma by upregulating BTG2 expression. | 0 |
| 31986889 | 2020 | Structural maintenance of chromosomes 2 is identified as an oncogene in bladder cancer in vitro and in vivo. | 5 |
| 31986889 | 2020 | Structural maintenance of chromosomes 2 is identified as an oncogene in bladder cancer in vitro and in vivo. | 5 |
| 30794721 | 2019 | Potential functional variants in SMC2 and TP53 in the AURORA pathway genes and risk of pancreatic cancer. | 16 |
| 30794721 | 2019 | Potential functional variants in SMC2 and TP53 in the AURORA pathway genes and risk of pancreatic cancer. | 16 |
| 26491021 | 2015 | Structural Basis for Dimer Formation of Human Condensin Structural Maintenance of Chromosome Proteins and Its Implications for Single-stranded DNA Recognition. | 10 |
| 26491021 | 2015 | Structural Basis for Dimer Formation of Human Condensin Structural Maintenance of Chromosome Proteins and Its Implications for Single-stranded DNA Recognition. | 10 |
| 24483990 | 2014 | Mutational and expressional analysis of SMC2 gene in gastric and colorectal cancers with microsatellite instability. | 9 |
| 24553121 | 2014 | Inactivation of SMC2 shows a synergistic lethal response in MYCN-amplified neuroblastoma cells. | 21 |
| 24483990 | 2014 | Mutational and expressional analysis of SMC2 gene in gastric and colorectal cancers with microsatellite instability. | 9 |
| 24553121 | 2014 | Inactivation of SMC2 shows a synergistic lethal response in MYCN-amplified neuroblastoma cells. | 21 |
| 23095742 | 2012 | Human SMC2 protein, a core subunit of human condensin complex, is a novel transcriptional target of the WNT signaling pathway and a new therapeutic target. | 33 |
| 23095742 | 2012 | Human SMC2 protein, a core subunit of human condensin complex, is a novel transcriptional target of the WNT signaling pathway and a new therapeutic target. | 33 |
| 20823528 | 2010 | Cloning, expression, crystallization and preliminary X-ray crystallographic analysis of a human condensin SMC2 hinge domain with short coiled coils. | 2 |
Citation
Dessen P
SMC2 (structural maintenance of chromosomes 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-11-01
Online version: http://atlasgeneticsoncology.org/gene/49801/smc2
