ACBD3 (acyl-CoA binding domain containing 3)

2007-12-01  

Identity

HGNC
LOCATION
1q42.12
LOCUSID
ALIAS
GCP60,GOCAP1,GOLPH1,PAP7
FUSION GENES

Other Information

Locus ID:

NCBI: 64746
MIM: 606809
HGNC: 15453
Ensembl: ENSG00000182827

Variants:

dbSNP: 64746
ClinVar: 64746
TCGA: ENSG00000182827
COSMIC: ACBD3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182827ENST00000366812Q9H3P7
ENSG00000182827ENST00000366812A0A024R3P9

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
trans-Golgi Network Vesicle BuddingREACTOMER-HSA-199992
Clathrin derived vesicle buddingREACTOMER-HSA-421837
Golgi Associated Vesicle BiogenesisREACTOMER-HSA-432722

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381342182024Recruitment of PI4KIIIβ to the Golgi by ACBD3 is dependent on an upstream pathway of a SNARE complex and golgins.0
381342182024Recruitment of PI4KIIIβ to the Golgi by ACBD3 is dependent on an upstream pathway of a SNARE complex and golgins.0
370442182023An A-kinase anchoring protein (ACBD3) coordinates traffic-induced PKA activation at the Golgi.1
371956332023The C10orf76-PI4KB axis orchestrates CERT-mediated ceramide trafficking to the distal Golgi.4
380980972023Identification of ACBD3 as a new molecular biomarker in pan-cancers through bioinformatic analysis: a preclinical study.0
370442182023An A-kinase anchoring protein (ACBD3) coordinates traffic-induced PKA activation at the Golgi.1
371956332023The C10orf76-PI4KB axis orchestrates CERT-mediated ceramide trafficking to the distal Golgi.4
380980972023Identification of ACBD3 as a new molecular biomarker in pan-cancers through bioinformatic analysis: a preclinical study.0
360121472022ACBD3 Bioinformatic Analysis and Protein Expression in Breast Cancer Cells.3
360121472022ACBD3 Bioinformatic Analysis and Protein Expression in Breast Cancer Cells.3
342988892021Knock-Out of ACBD3 Leads to Dispersed Golgi Structure, but Unaffected Mitochondrial Functions in HEK293 and HeLa Cells.2
343329832021ACBD3 is up-regulated in gastric cancer and promotes cell cycle G1-to-S transition in an AKT-dependent manner.1
342988892021Knock-Out of ACBD3 Leads to Dispersed Golgi Structure, but Unaffected Mitochondrial Functions in HEK293 and HeLa Cells.2
343329832021ACBD3 is up-regulated in gastric cancer and promotes cell cycle G1-to-S transition in an AKT-dependent manner.1
306796372019Phosphatidylinositol 4-kinase IIIβ (PI4KB) forms highly flexible heterocomplexes that include ACBD3, 14-3-3, and Rab11 proteins.10

Citation

Dessen P

ACBD3 (acyl-CoA binding domain containing 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-12-01

Online version: http://atlasgeneticsoncology.org/gene/49848/acbd3-(acyl-coa-binding-domain-containing-3)