STK11IP (serine/threonine kinase 11 interacting protein)

2007-12-01  

Identity

HGNC
STK11IP
LOCATION
2q35
LOCUSID
114790
ALIAS
LIP1,LKB1IP,STK11IP1

Other Information

Locus ID:

NCBI: 114790
MIM: 607172
HGNC: 19184
Ensembl: ENSG00000144589

Variants:

dbSNP: 114790
ClinVar: 114790
TCGA: ENSG00000144589
COSMIC: STK11IP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144589ENST00000413891H7C236
ENSG00000144589ENST00000447191H7C2J7
ENSG00000144589ENST00000456857E7ERV2
ENSG00000144589ENST00000456909Q8N1F8
ENSG00000144589ENST00000483319M0QYE5

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
334868942021LKB1IP promotes pathological cardiac hypertrophy by targeting PTEN/Akt signalling pathway.9
334868942021LKB1IP promotes pathological cardiac hypertrophy by targeting PTEN/Akt signalling pathway.9
209748502011Negative regulation of TGFβ signaling by the kinase LKB1 and the scaffolding protein LIP1.26
209748502011Negative regulation of TGFβ signaling by the kinase LKB1 and the scaffolding protein LIP1.26
175217002007Specific pattern of LKB1 and phospho-acetyl-CoA carboxylase protein immunostaining in human normal tissues and lung carcinomas.25
175217002007Specific pattern of LKB1 and phospho-acetyl-CoA carboxylase protein immunostaining in human normal tissues and lung carcinomas.25

Citation

Dessen P

STK11IP (serine/threonine kinase 11 interacting protein)

Atlas Genet Cytogenet Oncol Haematol. 2007-12-01

Online version: http://atlasgeneticsoncology.org/gene/49892/stk11ip-(serine-threonine-kinase-11-interacting-protein)