Identity
HGNC
LOCATION
12q13.3
LOCUSID
ALIAS
TIM,TIM1,hTIM
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8914
MIM: 603887
HGNC: 11813
Ensembl: ENSG00000111602
Variants:
dbSNP: 8914
ClinVar: 8914
TCGA: ENSG00000111602
COSMIC: TIMELESS
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000111602 | ENST00000229201 | Q9UNS1 |
| ENSG00000111602 | ENST00000553532 | Q9UNS1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38178094 | 2024 | TIMELESS promotes reprogramming of glucose metabolism in oral squamous cell carcinoma. | 0 |
| 38261568 | 2024 | ncRNAs-mediated TIMELESS overexpression in lung adenocarcinoma correlates with reduced tumor immune cell infiltration and poor prognosis. | 0 |
| 38354174 | 2024 | SP3-induced Timeless transcription contributes to cell growth of lung adenocarcinoma cells. | 0 |
| 38801073 | 2024 | The TIMELESS and PARP1 interaction suppresses replication-associated DNA gap accumulation. | 0 |
| 38178094 | 2024 | TIMELESS promotes reprogramming of glucose metabolism in oral squamous cell carcinoma. | 0 |
| 38261568 | 2024 | ncRNAs-mediated TIMELESS overexpression in lung adenocarcinoma correlates with reduced tumor immune cell infiltration and poor prognosis. | 0 |
| 38354174 | 2024 | SP3-induced Timeless transcription contributes to cell growth of lung adenocarcinoma cells. | 0 |
| 38801073 | 2024 | The TIMELESS and PARP1 interaction suppresses replication-associated DNA gap accumulation. | 0 |
| 36099062 | 2023 | Regulation of mineralocorticoid receptor activation by circadian protein TIMELESS. | 0 |
| 37144518 | 2023 | Replisome dysfunction upon inducible TIMELESS degradation synergizes with ATR inhibition to trigger replication catastrophe. | 3 |
| 37340461 | 2023 | TIMELESS upregulates PD-L1 expression and exerts an immunosuppressive role in breast cancer. | 1 |
| 37433364 | 2023 | TIMELESS promotes the proliferation and migration of lung adenocarcinoma cells by activating EGFR through AMPK and SPHK1 regulation. | 2 |
| 38053143 | 2023 | An integrative evaluation of circadian gene TIMELESS as a pan-cancer immunological and predictive biomarker. | 0 |
| 36099062 | 2023 | Regulation of mineralocorticoid receptor activation by circadian protein TIMELESS. | 0 |
| 37144518 | 2023 | Replisome dysfunction upon inducible TIMELESS degradation synergizes with ATR inhibition to trigger replication catastrophe. | 3 |
Citation
Dessen P
TIMELESS (timeless circadian regulator)
Atlas Genet Cytogenet Oncol Haematol. 2007-12-01
Online version: http://atlasgeneticsoncology.org/gene/49895/timeless
