Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84867
MIM: 176879
HGNC: 9657
Ensembl: ENSG00000110786
Variants:
dbSNP: 84867
ClinVar: 84867
TCGA: ENSG00000110786
COSMIC: PTPN5
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| MAPK signaling pathway | KEGG | ko04010 |
| MAPK signaling pathway | KEGG | hsa04010 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36639708 | 2023 | Tyrosine phosphatase STEP(61) in human dementia and in animal models with amyloid and tau pathology. | 1 |
| 36639708 | 2023 | Tyrosine phosphatase STEP(61) in human dementia and in animal models with amyloid and tau pathology. | 1 |
| 34270805 | 2021 | PTPN5 promotes follicle-stimulating hormone secretion through regulating intracellular calcium homeostasis. | 3 |
| 34270805 | 2021 | PTPN5 promotes follicle-stimulating hormone secretion through regulating intracellular calcium homeostasis. | 3 |
| 32461127 | 2020 | Inhibition of striatal-enriched protein tyrosine phosphatase (STEP) activity reverses behavioral deficits in a rodent model of autism. | 1 |
| 32461127 | 2020 | Inhibition of striatal-enriched protein tyrosine phosphatase (STEP) activity reverses behavioral deficits in a rodent model of autism. | 1 |
| 31135041 | 2019 | Loss of STEP61 couples disinhibition to N-methyl-d-aspartate receptor potentiation in rodent and human spinal pain processing. | 33 |
| 31135041 | 2019 | Loss of STEP61 couples disinhibition to N-methyl-d-aspartate receptor potentiation in rodent and human spinal pain processing. | 33 |
| 28389375 | 2017 | Striatal-enriched phosphatase 61 inhibited the nociceptive plasticity in spinal cord dorsal horn of rats. | 2 |
| 28528695 | 2017 | Protein phosphatase 5 promotes hepatocarcinogenesis through interaction with AMP-activated protein kinase. | 12 |
| 28675297 | 2017 | A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling. | 9 |
| 28699511 | 2017 | Striatal-enriched Tyrosine Protein Phosphatase (STEP) in the Mechanisms of Depressive Disorders. | 11 |
| 28389375 | 2017 | Striatal-enriched phosphatase 61 inhibited the nociceptive plasticity in spinal cord dorsal horn of rats. | 2 |
| 28528695 | 2017 | Protein phosphatase 5 promotes hepatocarcinogenesis through interaction with AMP-activated protein kinase. | 12 |
| 28675297 | 2017 | A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling. | 9 |
Citation
Dessen P
PTPN5 (protein tyrosine phosphatase non-receptor type 5)
Atlas Genet Cytogenet Oncol Haematol. 2007-12-01
Online version: http://atlasgeneticsoncology.org/gene/49904/ptpn5-(protein-tyrosine-phosphatase-non-receptor-type-5)
