Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5148
MIM: 180073
HGNC: 8789
Ensembl: ENSG00000185527
Variants:
dbSNP: 5148
ClinVar: 5148
TCGA: ENSG00000185527
COSMIC: PDE6G
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000185527 | ENST00000331056 | P18545 |
| ENSG00000185527 | ENST00000571004 | P18545 |
| ENSG00000185527 | ENST00000571224 | P18545 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 20397626 | 2010 | Determinants for phosphodiesterase 6 inhibition by its gamma-subunit. | 7 |
| 20655036 | 2010 | Autosomal-recessive early-onset retinitis pigmentosa caused by a mutation in PDE6G, the gene encoding the gamma subunit of rod cGMP phosphodiesterase. | 47 |
| 20979602 | 2010 | Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. | 10 |
| 20397626 | 2010 | Determinants for phosphodiesterase 6 inhibition by its gamma-subunit. | 7 |
| 20655036 | 2010 | Autosomal-recessive early-onset retinitis pigmentosa caused by a mutation in PDE6G, the gene encoding the gamma subunit of rod cGMP phosphodiesterase. | 47 |
| 20979602 | 2010 | Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. | 10 |
| 19798052 | 2009 | Structural basis of phosphodiesterase 6 inhibition by the C-terminal region of the gamma-subunit. | 42 |
| 19798052 | 2009 | Structural basis of phosphodiesterase 6 inhibition by the C-terminal region of the gamma-subunit. | 42 |
| 12624098 | 2003 | The inhibitory gamma subunit of the type 6 retinal cGMP phosphodiesterase functions to link c-Src and G-protein-coupled receptor kinase 2 in a signaling unit that regulates p42/p44 mitogen-activated protein kinase by epidermal growth factor. | 14 |
| 12624098 | 2003 | The inhibitory gamma subunit of the type 6 retinal cGMP phosphodiesterase functions to link c-Src and G-protein-coupled receptor kinase 2 in a signaling unit that regulates p42/p44 mitogen-activated protein kinase by epidermal growth factor. | 14 |
Citation
Dessen P
PDE6G (phosphodiesterase 6G)
Atlas Genet Cytogenet Oncol Haematol. 2007-12-01
Online version: http://atlasgeneticsoncology.org/gene/49914/pde6g-(phosphodiesterase-6g)
