Identity
HGNC
LOCATION
Xp22.12
LOCUSID
ALIAS
ASK3,bA723P2.3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 389840
MIM: 300820
HGNC: 31689
Ensembl: ENSG00000180815
Variants:
dbSNP: 389840
ClinVar: 389840
TCGA: ENSG00000180815
COSMIC: MAP3K15
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000180815 | ENST00000338883 | Q6ZN16 |
| ENSG00000180815 | ENST00000359173 | A0A140T8W5 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36383675 | 2022 | Human genetics uncovers MAP3K15 as an obesity-independent therapeutic target for diabetes. | 10 |
| 36383675 | 2022 | Human genetics uncovers MAP3K15 as an obesity-independent therapeutic target for diabetes. | 10 |
| 33649309 | 2021 | Cells recognize osmotic stress through liquid-liquid phase separation lubricated with poly(ADP-ribose). | 33 |
| 33649309 | 2021 | Cells recognize osmotic stress through liquid-liquid phase separation lubricated with poly(ADP-ribose). | 33 |
| 32156783 | 2020 | Structure-based mechanism of preferential complex formation by apoptosis signal-regulating kinases. | 9 |
| 32156783 | 2020 | Structure-based mechanism of preferential complex formation by apoptosis signal-regulating kinases. | 9 |
| 29539411 | 2018 | A PP6-ASK3 Module Coordinates the Bidirectional Cell Volume Regulation under Osmotic Stress. | 15 |
| 29539411 | 2018 | A PP6-ASK3 Module Coordinates the Bidirectional Cell Volume Regulation under Osmotic Stress. | 15 |
| 20362554 | 2010 | ASK3, a novel member of the apoptosis signal-regulating kinase family, is essential for stress-induced cell death in HeLa cells. | 17 |
| 20362554 | 2010 | ASK3, a novel member of the apoptosis signal-regulating kinase family, is essential for stress-induced cell death in HeLa cells. | 17 |
Citation
Dessen P
MAP3K15 (mitogen-activated protein kinase kinase kinase 15)
Atlas Genet Cytogenet Oncol Haematol. 2007-12-01
Online version: http://atlasgeneticsoncology.org/gene/49916/map3k15-(mitogen-activated-protein-kinase-kinase-kinase-15)
