Identity
HGNC
LOCATION
5q31.3
LOCUSID
ALIAS
CMT2W,HARS,HRS,USH3B
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3035
MIM: 142810
HGNC: 4816
Ensembl: ENSG00000170445
Variants:
dbSNP: 3035
ClinVar: 3035
TCGA: ENSG00000170445
COSMIC: HARS1
RNA/Proteins
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31797905 | 2021 | Serum-circulating His-tRNA synthetase inhibits organ-targeted immune responses. | 16 |
| 31797905 | 2021 | Serum-circulating His-tRNA synthetase inhibits organ-targeted immune responses. | 16 |
| 31982271 | 2020 | Serological risk factors for concomitant interstitial lung disease in patients with idiopathic inflammatory myopathy. | 4 |
| 32333447 | 2020 | Bi-allelic mutations in HARS1 severely impair histidyl-tRNA synthetase expression and enzymatic activity causing a novel multisystem ataxic syndrome. | 9 |
| 31982271 | 2020 | Serological risk factors for concomitant interstitial lung disease in patients with idiopathic inflammatory myopathy. | 4 |
| 32333447 | 2020 | Bi-allelic mutations in HARS1 severely impair histidyl-tRNA synthetase expression and enzymatic activity causing a novel multisystem ataxic syndrome. | 9 |
| 29235198 | 2018 | Substrate interaction defects in histidyl-tRNA synthetase linked to dominant axonal peripheral neuropathy. | 26 |
| 29235198 | 2018 | Substrate interaction defects in histidyl-tRNA synthetase linked to dominant axonal peripheral neuropathy. | 26 |
| 28321488 | 2017 | Evolutionary gain of highly divergent tRNA specificities by two isoforms of human histidyl-tRNA synthetase. | 10 |
| 28632987 | 2017 | The Usher Syndrome Type IIIB Histidyl-tRNA Synthetase Mutation Confers Temperature Sensitivity. | 14 |
| 28321488 | 2017 | Evolutionary gain of highly divergent tRNA specificities by two isoforms of human histidyl-tRNA synthetase. | 10 |
| 28632987 | 2017 | The Usher Syndrome Type IIIB Histidyl-tRNA Synthetase Mutation Confers Temperature Sensitivity. | 14 |
| 26072516 | 2015 | Loss of function mutations in HARS cause a spectrum of inherited peripheral neuropathies. | 52 |
| 26072516 | 2015 | Loss of function mutations in HARS cause a spectrum of inherited peripheral neuropathies. | 52 |
| 23422076 | 2014 | Patients with non-Jo-1 anti-tRNA-synthetase autoantibodies have worse survival than Jo-1 positive patients. | 79 |
Citation
Dessen P
HARS1 (histidyl-tRNA synthetase 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-12-01
Online version: http://atlasgeneticsoncology.org/gene/49937/hars1-(histidyl-trna-synthetase-1)
