Identity
HGNC
LOCATION
1p36.21
LOCUSID
ALIAS
CAL,FBLP-1,FBLP1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54751
MIM: 607747
HGNC: 24686
Ensembl: ENSG00000162458
Variants:
dbSNP: 54751
ClinVar: 54751
TCGA: ENSG00000162458
COSMIC: FBLIM1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Cell-Cell communication | REACTOME | R-HSA-1500931 |
| Cell junction organization | REACTOME | R-HSA-446728 |
| Cell-extracellular matrix interactions | REACTOME | R-HSA-446353 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32397996 | 2020 | Genetic variants in FBLIM1 gene do not contribute to SAPHO syndrome and chronic recurrent multifocal osteomyelitis in typical patient groups. | 5 |
| 32650789 | 2020 | High prevalence of rare FBLIM1 gene variants in an Italian cohort of patients with Chronic Non-bacterial Osteomyelitis (CNO). | 4 |
| 32397996 | 2020 | Genetic variants in FBLIM1 gene do not contribute to SAPHO syndrome and chronic recurrent multifocal osteomyelitis in typical patient groups. | 5 |
| 32650789 | 2020 | High prevalence of rare FBLIM1 gene variants in an Italian cohort of patients with Chronic Non-bacterial Osteomyelitis (CNO). | 4 |
| 29114925 | 2018 | Possible involvement of a cell adhesion molecule, Migfilin, in brain development and pathogenesis of autism spectrum disorders. | 5 |
| 30053867 | 2018 | circFBLIM1 act as a ceRNA to promote hepatocellular cancer progression by sponging miR-346. | 98 |
| 30129678 | 2018 | FBLIM1 enhances oral cancer malignancy via modulation of the epidermal growth factor receptor pathway. | 10 |
| 29114925 | 2018 | Possible involvement of a cell adhesion molecule, Migfilin, in brain development and pathogenesis of autism spectrum disorders. | 5 |
| 30053867 | 2018 | circFBLIM1 act as a ceRNA to promote hepatocellular cancer progression by sponging miR-346. | 98 |
| 30129678 | 2018 | FBLIM1 enhances oral cancer malignancy via modulation of the epidermal growth factor receptor pathway. | 10 |
| 28301468 | 2017 | Recessive coding and regulatory mutations in FBLIM1 underlie the pathogenesis of chronic recurrent multifocal osteomyelitis (CRMO). | 35 |
| 29203120 | 2017 | Migfilin promotes migration and invasion in glioma by driving EGFR and MMP-2 signalings: A positive feedback loop regulation. | 4 |
| 28301468 | 2017 | Recessive coding and regulatory mutations in FBLIM1 underlie the pathogenesis of chronic recurrent multifocal osteomyelitis (CRMO). | 35 |
| 29203120 | 2017 | Migfilin promotes migration and invasion in glioma by driving EGFR and MMP-2 signalings: A positive feedback loop regulation. | 4 |
| 23099104 | 2013 | Migfilin, α-parvin and β-parvin are differentially expressed in ovarian serous carcinoma effusions, primary tumors and solid metastases. | 2 |
Citation
Dessen P
FBLIM1 (filamin binding LIM protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2008-01-01
Online version: http://atlasgeneticsoncology.org/gene/49967/fblim1-(filamin-binding-lim-protein-1)
