LGALS2 (galectin 2)

2008-01-01  

Identity

HGNC
LOCATION
22q13.1
LOCUSID
ALIAS
HL14
FUSION GENES

Other Information

Locus ID:

NCBI: 3957
MIM: 150571
HGNC: 6562
Ensembl: ENSG00000100079

Variants:

dbSNP: 3957
ClinVar: 3957
TCGA: ENSG00000100079
COSMIC: LGALS2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100079ENST00000215886P05162
ENSG00000100079ENST00000416480B0QYC9

Expression (GTEx)

0
10
20
30
40
50
60
70

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
151292822004Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro.49
151292822004Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro.49
153561302004Human galectin-2: novel inducer of T cell apoptosis with distinct profile of caspase activation.48
169404232007Human galectin-1, -2, and -4 induce surface exposure of phosphatidylserine in activated human neutrophils but not in activated T cells.42
185063752008Association of genetic variants with atherothrombotic cerebral infarction in Japanese individuals with metabolic syndrome.24
185063752008Association of genetic variants with atherothrombotic cerebral infarction in Japanese individuals with metabolic syndrome.24
218319082012Galectin-2 expression is dependent on the rs7291467 polymorphism and acts as an inhibitor of arteriogenesis.22
217241802011Galectins distinctively regulate central monocyte and macrophage function.18

Citation

Dessen P

LGALS2 (galectin 2)

Atlas Genet Cytogenet Oncol Haematol. 2008-01-01

Online version: http://atlasgeneticsoncology.org/gene/49983/lgals2-(galectin-2)