CD96 (CD96 molecule)

2008-01-01  

Identity

HGNC
CD96
LOCATION
3q13.13
LOCUSID
10225
ALIAS
TACTILE
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10225
MIM: 606037
HGNC: 16892
Ensembl: ENSG00000153283

Variants:

dbSNP: 10225
ClinVar: 10225
TCGA: ENSG00000153283
COSMIC: CD96

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000153283ENST00000283285P40200
ENSG00000153283ENST00000352690P40200
ENSG00000153283ENST00000438817Q8WUE2
ENSG00000153283ENST00000460744U3KPT0
ENSG00000153283ENST00000465428H7C4F0
ENSG00000153283ENST00000488054F8WDV3
ENSG00000153283ENST00000494798E9PEJ1

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
359245752023Early expression of CD94 and loss of CD96 on CD8+ T cells after allogeneic stem cell tranplantation is predictive of subsequent relapse and survival.1
365814702023Tumor Cell-Intrinsic CD96 Mediates Chemoresistance and Cancer Stemness by Regulating Mitochondrial Fatty Acid β-Oxidation.8
366748172023CD96 as a Potential Immune Regulator in Cancers.2
369495732023CD44, CD90 and CD96 expression in immune thrombocytopenia purpura (ITP) patients.0
370757052023Deficiency of the CD155-CD96 immune checkpoint controls IL-9 production in giant cell arteritis.5
359245752023Early expression of CD94 and loss of CD96 on CD8+ T cells after allogeneic stem cell tranplantation is predictive of subsequent relapse and survival.1
365814702023Tumor Cell-Intrinsic CD96 Mediates Chemoresistance and Cancer Stemness by Regulating Mitochondrial Fatty Acid β-Oxidation.8
366748172023CD96 as a Potential Immune Regulator in Cancers.2
369495732023CD44, CD90 and CD96 expression in immune thrombocytopenia purpura (ITP) patients.0
370757052023Deficiency of the CD155-CD96 immune checkpoint controls IL-9 production in giant cell arteritis.5
360048182022Natural killer cell profiles in recurrent pregnancy loss: Increased expression and positive associations with TACTILE and LILRB1.5
360048182022Natural killer cell profiles in recurrent pregnancy loss: Increased expression and positive associations with TACTILE and LILRB1.5
329179812021Direct interaction between CD155 and CD96 promotes immunosuppression in lung adenocarcinoma.5
332982472021Hitting the complexity of the TIGIT-CD96-CD112R-CD226 axis for next-generation cancer immunotherapy.25
329179812021Direct interaction between CD155 and CD96 promotes immunosuppression in lung adenocarcinoma.5

Citation

Dessen P

CD96 (CD96 molecule)

Atlas Genet Cytogenet Oncol Haematol. 2008-01-01

Online version: http://atlasgeneticsoncology.org/gene/49991/cd96-(cd96-molecule)