NTF4 (neurotrophin 4)

2007-02-01 Affiliation

Identity

HGNC

NTF4

LOCATION

19q13.33

LOCUSID

4909

ALIAS

GLC10,GLC1O,NT-4,NT-4/5,NT-5,NT4,NT5,NTF5

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 4909
MIM: 162662
HGNC: 8024
Ensembl: ENSG00000225950

Variants:

dbSNP: 4909
ClinVar: 4909
TCGA: ENSG00000225950
COSMIC: NTF4

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000225950	ENST00000593537	P34130
ENSG00000225950	ENST00000593537	A0A024QZE4
ENSG00000225950	ENST00000595857	M0R0X2

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
MAPK signaling pathway	KEGG	ko04010
MAPK signaling pathway	KEGG	hsa04010
Neurotrophin signaling pathway	KEGG	ko04722
Neurotrophin signaling pathway	KEGG	hsa04722

References

Pubmed ID	Year	Title	Citations
15987945	2005	Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway.	138
19598235	2009	Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome.	92
19765683	2009	Heterozygous NTF4 mutations impairing neurotrophin-4 signaling in patients with primary open-angle glaucoma.	56
21350004	2011	Brain-derived neurotrophic factor and neurotrophin-4/5 are expressed in breast cancer and can be targeted to inhibit tumor cell survival.	46
18305571	2008	Neurotrophins and their receptors stimulate melanoma cell proliferation and migration.	45
19086053	2009	Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.	34
16648236	2006	Neurotrophin effects on intracellular Ca2+ and force in airway smooth muscle.	30
18179783	2008	Association study of 10 genes encoding neurotrophic factors and their receptors in adult and child attention-deficit/hyperactivity disorder.	24
20215012	2010	No evidence of association of heterozygous NTF4 mutations in patients with primary open-angle glaucoma.	24
20215012	2010	No evidence of association of heterozygous NTF4 mutations in patients with primary open-angle glaucoma.	24

Citation

Dessen P

NTF4 (neurotrophin 4)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/50016/ntf4-(neurotrophin-4)