Identity
HGNC
LOCATION
19p13.12
LOCUSID
ALIAS
CRL1,IL-27RA,IL27R,TCCR,WSX1,zcytor1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9466
MIM: 605350
HGNC: 17290
Ensembl: ENSG00000104998
Variants:
dbSNP: 9466
ClinVar: 9466
TCGA: ENSG00000104998
COSMIC: IL27RA
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000104998 | ENST00000263379 | Q6UWB1 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38509369 | 2024 | Role of IL-27 in Epstein-Barr virus infection revealed by IL-27RA deficiency. | 1 |
| 38509369 | 2024 | Role of IL-27 in Epstein-Barr virus infection revealed by IL-27RA deficiency. | 1 |
| 36867577 | 2023 | Cytokine receptor IL27RA is an NF-κB-responsive gene involved in CD38 upregulation in multiple myeloma. | 2 |
| 36867577 | 2023 | Cytokine receptor IL27RA is an NF-κB-responsive gene involved in CD38 upregulation in multiple myeloma. | 2 |
| 35723626 | 2022 | IL27 Signaling Serves as an Immunologic Checkpoint for Innate Cytotoxic Cells to Promote Hepatocellular Carcinoma. | 10 |
| 35920255 | 2022 | Structural insights into the assembly and activation of the IL-27 signaling complex. | 12 |
| 35723626 | 2022 | IL27 Signaling Serves as an Immunologic Checkpoint for Innate Cytotoxic Cells to Promote Hepatocellular Carcinoma. | 10 |
| 35920255 | 2022 | Structural insights into the assembly and activation of the IL-27 signaling complex. | 12 |
| 34108491 | 2021 | WSX1 act as a tumor suppressor in hepatocellular carcinoma by downregulating neoplastic PD-L1 expression. | 20 |
| 34108491 | 2021 | WSX1 act as a tumor suppressor in hepatocellular carcinoma by downregulating neoplastic PD-L1 expression. | 20 |
| 32522836 | 2020 | Loss of IL-27Rα Results in Enhanced Tubulointerstitial Fibrosis Associated with Elevated Th17 Responses. | 8 |
| 32522836 | 2020 | Loss of IL-27Rα Results in Enhanced Tubulointerstitial Fibrosis Associated with Elevated Th17 Responses. | 8 |
| 28592538 | 2017 | Identification of Interleukin-27 (IL-27)/IL-27 Receptor Subunit Alpha as a Critical Immune Axis for In Vivo HIV Control. | 15 |
| 28756371 | 2017 | IL-27 induces a pro-inflammatory response in human fetal membranes mediating preterm birth. | 7 |
| 28592538 | 2017 | Identification of Interleukin-27 (IL-27)/IL-27 Receptor Subunit Alpha as a Critical Immune Axis for In Vivo HIV Control. | 15 |
Citation
Dessen P
IL27RA (interleukin 27 receptor subunit alpha)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/50022/il27ra-(interleukin-27-receptor-subunit-alpha)
