Identity
HGNC
LOCATION
Xp21.3
LOCUSID
ALIAS
IL-1-RAPL-1,IL-1RAPL-1,IL1R8,IL1RAPL,IL1RAPL-1,MRX10,MRX21,MRX34,OPHN4,TIGIRR-2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11141
MIM: 300206
HGNC: 5996
Ensembl: ENSG00000169306
Variants:
dbSNP: 11141
ClinVar: 11141
TCGA: ENSG00000169306
COSMIC: IL1RAPL1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000169306 | ENST00000302196 | A0A0A0MR17 |
| ENSG00000169306 | ENST00000378993 | Q9NZN1 |
| ENSG00000169306 | ENST00000378993 | X5DNQ7 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37907630 | 2023 | IL-1R8 expression in DLBCL regulates NK cell recruitment and influences patient prognosis. | 1 |
| 37907630 | 2023 | IL-1R8 expression in DLBCL regulates NK cell recruitment and influences patient prognosis. | 1 |
| 36318984 | 2022 | RGS3 and IL1RAPL1 missense variants implicate defective neurotransmission in early-onset inherited schizophrenias. | 1 |
| 36318984 | 2022 | RGS3 and IL1RAPL1 missense variants implicate defective neurotransmission in early-onset inherited schizophrenias. | 1 |
| 30548231 | 2019 | The Synaptic and Neuronal Functions of the X-Linked Intellectual Disability Protein Interleukin-1 Receptor Accessory Protein Like 1 (IL1RAPL1). | 15 |
| 30548231 | 2019 | The Synaptic and Neuronal Functions of the X-Linked Intellectual Disability Protein Interleukin-1 Receptor Accessory Protein Like 1 (IL1RAPL1). | 15 |
| 29730558 | 2018 | Increased expression of IL-1R8 and a possible immunomodulatory role of its ligand IL-37 in allergic rhinitis patients. | 4 |
| 29730558 | 2018 | Increased expression of IL-1R8 and a possible immunomodulatory role of its ligand IL-37 in allergic rhinitis patients. | 4 |
| 28120837 | 2017 | Suggestive association between variants in IL1RAPL and asthma symptoms in Latin American children. | 8 |
| 29072292 | 2017 | IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity. | 117 |
| 28120837 | 2017 | Suggestive association between variants in IL1RAPL and asthma symptoms in Latin American children. | 8 |
| 29072292 | 2017 | IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity. | 117 |
| 27440233 | 2016 | Preliminary assessment of pre-morbid DNA methylation in individuals at high genetic risk of mood disorders. | 8 |
| 27470653 | 2016 | Clinical and molecular characterization of a boy with intellectual disability, facial dysmorphism, minor digital anomalies and a complex IL1RAPL1 intragenic rearrangement. | 3 |
| 27440233 | 2016 | Preliminary assessment of pre-morbid DNA methylation in individuals at high genetic risk of mood disorders. | 8 |
Citation
Dessen P
IL1RAPL1 (interleukin 1 receptor accessory protein like 1)
Atlas Genet Cytogenet Oncol Haematol. 2008-03-01
Online version: http://atlasgeneticsoncology.org/gene/50038/il1rapl1
