Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9542
MIM: 603818
HGNC: 7998
Ensembl: ENSG00000158458
Variants:
dbSNP: 9542
ClinVar: 9542
TCGA: ENSG00000158458
COSMIC: NRG2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10040 | cetuximab | Chemical | Pathway | associated | |||
| PA162373091 | panitumumab | Chemical | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34996744 | 2022 | NRG1 and NRG2 fusion positive solid tumor malignancies: a paradigm of ligand-fusion oncogenesis. | 13 |
| 36411648 | 2022 | The relevance of EGFR, ErbB receptors and neuregulins in human adipocytes and adipose tissue in obesity. | 3 |
| 34996744 | 2022 | NRG1 and NRG2 fusion positive solid tumor malignancies: a paradigm of ligand-fusion oncogenesis. | 13 |
| 36411648 | 2022 | The relevance of EGFR, ErbB receptors and neuregulins in human adipocytes and adipose tissue in obesity. | 3 |
| 34284546 | 2021 | Neuregulin 2 (NRG2) is expressed in gliomas and promotes migration of human glioma cells. | 2 |
| 34549707 | 2021 | [Neuregulin 2 is highly expressed in glioma tissues to regulate glial fibrillary acidic protein expression via Akt signaling]. | 0 |
| 34284546 | 2021 | Neuregulin 2 (NRG2) is expressed in gliomas and promotes migration of human glioma cells. | 2 |
| 34549707 | 2021 | [Neuregulin 2 is highly expressed in glioma tissues to regulate glial fibrillary acidic protein expression via Akt signaling]. | 0 |
| 33378376 | 2020 | Development and application of high-throughput screens for the discovery of compounds that disrupt ErbB4 signaling: Candidate cancer therapeutics. | 1 |
| 33378376 | 2020 | Development and application of high-throughput screens for the discovery of compounds that disrupt ErbB4 signaling: Candidate cancer therapeutics. | 1 |
| 27345716 | 2016 | Identification of Neuregulin-2 as a novel stress granule component. | 2 |
| 27345716 | 2016 | Identification of Neuregulin-2 as a novel stress granule component. | 2 |
| 19086053 | 2009 | Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. | 39 |
| 19086053 | 2009 | Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. | 39 |
| 17962208 | 2008 | ErbB/HER ligands in human breast cancer, and relationships with their receptors, the bio-pathological features and prognosis. | 59 |
Citation
Dessen P
NRG2 (neuregulin 2)
Atlas Genet Cytogenet Oncol Haematol. 2008-03-01
Online version: http://atlasgeneticsoncology.org/gene/50050/nrg2-(neuregulin-2)
