Identity
HGNC
LOCATION
15q23
LOCUSID
ALIAS
ESG,ESG3,GRG3,HsT18976
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7090
MIM: 600190
HGNC: 11839
Ensembl: ENSG00000140332
Variants:
dbSNP: 7090
ClinVar: 7090
TCGA: ENSG00000140332
COSMIC: TLE3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38177411 | 2024 | The Wnt-pathway corepressor TLE3 interacts with the histone methyltransferase KMT1A to inhibit differentiation in Rhabdomyosarcoma. | 0 |
| 38177411 | 2024 | The Wnt-pathway corepressor TLE3 interacts with the histone methyltransferase KMT1A to inhibit differentiation in Rhabdomyosarcoma. | 0 |
| 37302518 | 2023 | HHEX suppresses advanced thyroid cancer by interacting with TLE3. | 3 |
| 37302518 | 2023 | HHEX suppresses advanced thyroid cancer by interacting with TLE3. | 3 |
| 33571907 | 2021 | Differential functions of TLE1 and TLE3 depending on a specific phosphorylation site. | 1 |
| 34551306 | 2021 | Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia. | 9 |
| 33571907 | 2021 | Differential functions of TLE1 and TLE3 depending on a specific phosphorylation site. | 1 |
| 34551306 | 2021 | Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia. | 9 |
| 31855178 | 2019 | TLE3 loss confers AR inhibitor resistance by facilitating GR-mediated human prostate cancer cell growth. | 18 |
| 31855178 | 2019 | TLE3 loss confers AR inhibitor resistance by facilitating GR-mediated human prostate cancer cell growth. | 18 |
| 29374067 | 2018 | RNF6 Promotes Colorectal Cancer by Activating the Wnt/β-Catenin Pathway via Ubiquitination of TLE3. | 48 |
| 29374067 | 2018 | RNF6 Promotes Colorectal Cancer by Activating the Wnt/β-Catenin Pathway via Ubiquitination of TLE3. | 48 |
| 28107193 | 2017 | MicroRNA-744 promotes prostate cancer progression through aberrantly activating Wnt/β-catenin signaling. | 27 |
| 28689657 | 2017 | Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5. | 37 |
| 28859615 | 2017 | Identification of predictive markers of the therapeutic effect of eribulin chemotherapy for locally advanced or metastatic breast cancer. | 9 |
Citation
Dessen P
TLE3 (TLE family member 3, transcriptional corepressor)
Atlas Genet Cytogenet Oncol Haematol. 2008-03-01
Online version: http://atlasgeneticsoncology.org/gene/50058/tle3-(tle-family-member-3-transcriptional-corepressor)
