Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2266
MIM: 134850
HGNC: 3694
Ensembl: ENSG00000171557
Variants:
dbSNP: 2266
ClinVar: 2266
TCGA: ENSG00000171557
COSMIC: FGG
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA448006 | abciximab | Chemical | Pathway | associated | 20938371 | ||
| PA449483 | eptifibatide | Chemical | Pathway | associated | 20938371 | ||
| PA451698 | tirofiban | Chemical | Pathway | associated | 20938371 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38233949 | 2024 | A novel missense mutation (FGG c.1168G > T) in the gamma chain of fibrinogen causing congenital hypodysfibrinogenemia with bleeding phenotype. | 0 |
| 38374144 | 2024 | A novel mutation in the FGG gene causes hypofibrinogenemia in a Chinese family. | 0 |
| 38233949 | 2024 | A novel missense mutation (FGG c.1168G > T) in the gamma chain of fibrinogen causing congenital hypodysfibrinogenemia with bleeding phenotype. | 0 |
| 38374144 | 2024 | A novel mutation in the FGG gene causes hypofibrinogenemia in a Chinese family. | 0 |
| 36599322 | 2023 | Two Novel Heterozygous Mutations (p.γPhe230Val and p.AαAsn839Thr) Cause Hereditary Hypodysfibrinogenemia in Two Chinese Independent Families. | 0 |
| 37076872 | 2023 | Genome-wide association analyses identified novel susceptibility loci for pulmonary embolism among Han Chinese population. | 11 |
| 37906135 | 2023 | [Genetic analysis of a Chinese pedigree affected with Congenital dysfibrinogenemia due to variant of FGG gene]. | 0 |
| 36599322 | 2023 | Two Novel Heterozygous Mutations (p.γPhe230Val and p.AαAsn839Thr) Cause Hereditary Hypodysfibrinogenemia in Two Chinese Independent Families. | 0 |
| 37076872 | 2023 | Genome-wide association analyses identified novel susceptibility loci for pulmonary embolism among Han Chinese population. | 11 |
| 37906135 | 2023 | [Genetic analysis of a Chinese pedigree affected with Congenital dysfibrinogenemia due to variant of FGG gene]. | 0 |
| 32877852 | 2021 | Identification and characterization of novel mutations in Chinese patients with congenital fibrinogen disorders. | 0 |
| 33276061 | 2021 | Thermal shift assay to probe melting of thrombin, fibrinogen, fibrin monomer, and fibrin: Gly-Pro-Arg-Pro induces a fibrin monomer-like state in fibrinogen. | 3 |
| 33682960 | 2021 | Changes and significance of plasma fibrinogen gamma-chain concentration in preeclampsia patients. | 1 |
| 33864425 | 2021 | Plasma proteomics analysis of adolescent idiopathic scoliosis patients revealed by Quadrupole-Orbitrap mass spectrometry. | 2 |
| 34069309 | 2021 | Recombinant γY278H Fibrinogen Showed Normal Secretion from CHO Cells, but a Corresponding Heterozygous Patient Showed Hypofibrinogenemia. | 0 |
Citation
Dessen P
FGG (fibrinogen gamma chain)
Atlas Genet Cytogenet Oncol Haematol. 2008-03-01
Online version: http://atlasgeneticsoncology.org/gene/50068/fgg-(fibrinogen-gamma-chain)
