Identity
HGNC
LOCATION
9q21.2
LOCUSID
ALIAS
EPIP,NLS2,PSA,PSAT,PSATD
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 29968
MIM: 610936
HGNC: 19129
Ensembl: ENSG00000135069
Variants:
dbSNP: 29968
ClinVar: 29968
TCGA: ENSG00000135069
COSMIC: PSAT1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000135069 | ENST00000347159 | Q9Y617 |
| ENSG00000135069 | ENST00000347159 | A0A024R280 |
| ENSG00000135069 | ENST00000376588 | Q9Y617 |
| ENSG00000135069 | ENST00000376588 | A0A024R222 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37832835 | 2024 | PSAT1 promotes autophagy to resist insufficient autophagy caused by cigarette smoke extract in human airway epithelial cells. | 0 |
| 38373588 | 2024 | Upregulation of serine metabolism enzyme PSAT1 predicts poor prognosis and promotes proliferation, metastasis and drug resistance of clear cell renal cell carcinoma. | 0 |
| 37832835 | 2024 | PSAT1 promotes autophagy to resist insufficient autophagy caused by cigarette smoke extract in human airway epithelial cells. | 0 |
| 38373588 | 2024 | Upregulation of serine metabolism enzyme PSAT1 predicts poor prognosis and promotes proliferation, metastasis and drug resistance of clear cell renal cell carcinoma. | 0 |
| 36371491 | 2023 | miRNA-195-5p/PSAT1 feedback loop in human triple-negative breast cancer cells. | 3 |
| 36599231 | 2023 | Pathogenic PSAT1 Variants and Autosomal Recessive Axonal Charcot-Marie-Tooth Disease With Ichthyosis. | 0 |
| 36788227 | 2023 | Targeting PSAT1 to mitigate metastasis in tumors with p53-72Pro variant. | 9 |
| 36851825 | 2023 | L-serine biosynthesis in the human central nervous system: Structure and function of phosphoserine aminotransferase. | 7 |
| 36906716 | 2023 | Downregulation of PSAT1 inhibits cell proliferation and migration in uterine corpus endometrial carcinoma. | 3 |
| 37192746 | 2023 | Exosomal ERBB2IP contributes to tumor growth via elevating PSAT1 expression in non-small cell lung carcinoma. | 5 |
| 37627284 | 2023 | Phosphoserine Aminotransferase Pathogenetic Variants in Serine Deficiency Disorders: A Functional Characterization. | 0 |
| 37919070 | 2023 | Overexpression of PSAT1 is Correlated with Poor Prognosis and Immune Infiltration in Non-Small Cell Lung Cancer. | 1 |
| 36371491 | 2023 | miRNA-195-5p/PSAT1 feedback loop in human triple-negative breast cancer cells. | 3 |
| 36599231 | 2023 | Pathogenic PSAT1 Variants and Autosomal Recessive Axonal Charcot-Marie-Tooth Disease With Ichthyosis. | 0 |
| 36788227 | 2023 | Targeting PSAT1 to mitigate metastasis in tumors with p53-72Pro variant. | 9 |
Citation
Dessen P
PSAT1 (phosphoserine aminotransferase 1)
Atlas Genet Cytogenet Oncol Haematol. 2008-03-01
Online version: http://atlasgeneticsoncology.org/gene/50075/psat1
