SOX1 (SRY-box transcription factor 1)

2008-05-01  

Identity

HGNC
LOCATION
13q34
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 6656
MIM: 602148
HGNC: 11189
Ensembl: ENSG00000182968

Variants:

dbSNP: 6656
ClinVar: 6656
TCGA: ENSG00000182968
COSMIC: SOX1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182968ENST00000330949O00570

Expression (GTEx)

0
1
2
3
4
5
6

References

Pubmed IDYearTitleCitations
95125121998Sox1 directly regulates the gamma-crystallin genes and is essential for lens development in mice.82
151107212004Sox1 acts through multiple independent pathways to promote neurogenesis.57
196672722009SOX antibodies in small-cell lung cancer and Lambert-Eaton myasthenic syndrome: frequency and relation with survival.41
228602172012DMH1, a highly selective small molecule BMP inhibitor promotes neurogenesis of hiPSCs: comparison of PAX6 and SOX1 expression during neural induction.39
180327432008SOX1 antibodies are markers of paraneoplastic Lambert-Eaton myasthenic syndrome.33
227671862012SOX1 functions as a tumor suppressor by antagonizing the WNT/β-catenin signaling pathway in hepatocellular carcinoma.32
263651942015Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells.29
244075762014High methylation rate of LMX1A, NKX6-1, PAX1, PTPRR, SOX1, and ZNF582 genes in cervical adenocarcinoma.25
208441232010Sox1 is required for the specification of a novel p2-derived interneuron subtype in the mouse ventral spinal cord.24
206348912010Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.18

Citation

Dessen P

SOX1 (SRY-box transcription factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2008-05-01

Online version: http://atlasgeneticsoncology.org/gene/50115/sox1-(sry-box-transcription-factor-1)