Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 200315
MIM: 607109
HGNC: 17343
Ensembl: ENSG00000128383
Variants:
dbSNP: 200315
ClinVar: 200315
TCGA: ENSG00000128383
COSMIC: APOBEC3A
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| mRNA Editing | REACTOME | R-HSA-75072 |
| mRNA Editing: C to U Conversion | REACTOME | R-HSA-72200 |
| Formation of the Editosome | REACTOME | R-HSA-75094 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38499553 | 2024 | Distinguishing preferences of human APOBEC3A and APOBEC3B for cytosines in hairpin loops, and reflection of these preferences in APOBEC-signature cancer genome mutations. | 2 |
| 38499553 | 2024 | Distinguishing preferences of human APOBEC3A and APOBEC3B for cytosines in hairpin loops, and reflection of these preferences in APOBEC-signature cancer genome mutations. | 2 |
| 36394079 | 2023 | APOBEC3A/B deletion polymorphism and endometrial cancer risk. | 1 |
| 36610792 | 2023 | Cellular APOBEC3A deaminase drives mutations in the SARS-CoV-2 genome. | 17 |
| 36889736 | 2023 | The role of APOBEC3A in cervical cancer development and progression: A retrospective study. | 2 |
| 37154747 | 2023 | Apobec3A Deamination Functions Are Involved in Antagonizing Efficient Human Adenovirus Replication and Gene Expression. | 3 |
| 37282621 | 2023 | Seven-membered ring nucleobases as inhibitors of human cytidine deaminase and APOBEC3A. | 3 |
| 37298259 | 2023 | DNA Deamination Is Required for Human APOBEC3A-Driven Hepatocellular Carcinoma In Vivo. | 7 |
| 37407818 | 2023 | Therapy-induced APOBEC3A drives evolution of persistent cancer cells. | 21 |
| 37442413 | 2023 | Unraveling the Enzyme-Substrate Properties for APOBEC3A-Mediated RNA Editing. | 3 |
| 37474103 | 2023 | Mitochondrial double-stranded RNA triggers induction of the antiviral DNA deaminase APOBEC3A and nuclear DNA damage. | 1 |
| 38033156 | 2023 | Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer. | 8 |
| 38105291 | 2023 | Regulatory variants of APOBEC3 genes potentially associate with COVID-19 severity in populations with African ancestry. | 0 |
| 36394079 | 2023 | APOBEC3A/B deletion polymorphism and endometrial cancer risk. | 1 |
| 36610792 | 2023 | Cellular APOBEC3A deaminase drives mutations in the SARS-CoV-2 genome. | 17 |
Citation
Dessen P
APOBEC3A (apolipoprotein B mRNA editing enzyme catalytic subunit 3A)
Atlas Genet Cytogenet Oncol Haematol. 2008-05-01
Online version: http://atlasgeneticsoncology.org/gene/50116/apobec3a-(apolipoprotein-b-mrna-editing-enzyme-catalytic-subunit-3a)
