Identity
HGNC
LOCATION
19q13.33
LOCUSID
ALIAS
ADTAA,AP2-ALPHA,CLAPA1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 160
MIM: 601026
HGNC: 561
Ensembl: ENSG00000196961
Variants:
dbSNP: 160
ClinVar: 160
TCGA: ENSG00000196961
COSMIC: AP2A1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000196961 | ENST00000354293 | O95782 |
| ENSG00000196961 | ENST00000359032 | O95782 |
| ENSG00000196961 | ENST00000597774 | M0R2D9 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30081190 | 2018 | Molecular cloning of novel transcripts of the adaptor-related protein complex 2 alpha 1 subunit (AP2A1) gene, using Next-Generation Sequencing. | 2 |
| 30081190 | 2018 | Molecular cloning of novel transcripts of the adaptor-related protein complex 2 alpha 1 subunit (AP2A1) gene, using Next-Generation Sequencing. | 2 |
| 28577469 | 2017 | The interaction between HIV-1 Nef and adaptor protein-2 reduces Nef-mediated CD4(+) T cell apoptosis. | 13 |
| 28577469 | 2017 | The interaction between HIV-1 Nef and adaptor protein-2 reduces Nef-mediated CD4(+) T cell apoptosis. | 13 |
| 24473078 | 2014 | How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4. | 78 |
| 24473078 | 2014 | How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4. | 78 |
| 22360420 | 2012 | Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration. | 24 |
| 22360420 | 2012 | Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration. | 24 |
| 18178234 | 2008 | Inhibitory function of adapter-related protein complex 2 alpha 1 subunit in the process of nuclear translocation of human immunodeficiency virus type 1 genome. | 7 |
| 18524831 | 2008 | Competition model for upregulation of the major histocompatibility complex class II-associated invariant chain by human immunodeficiency virus type 1 Nef. | 8 |
| 18178234 | 2008 | Inhibitory function of adapter-related protein complex 2 alpha 1 subunit in the process of nuclear translocation of human immunodeficiency virus type 1 genome. | 7 |
| 18524831 | 2008 | Competition model for upregulation of the major histocompatibility complex class II-associated invariant chain by human immunodeficiency virus type 1 Nef. | 8 |
Citation
Dessen P
AP2A1 (adaptor related protein complex 2 subunit alpha 1)
Atlas Genet Cytogenet Oncol Haematol. 2008-05-01
Online version: http://atlasgeneticsoncology.org/gene/50118/ap2a1-(adaptor-related-protein-complex-2-subunit-alpha-1)
