MIR223 (microRNA 223)

2008-07-01  

Identity

HGNC
MIR223
LOCATION
Xq12
LOCUSID
407008
ALIAS
MIRN223,miRNA223,mir-223

Other Information

Locus ID:

NCBI: 407008
MIM: 300694
HGNC: 31603
Ensembl: ENSG00000284567
miRBase:

Variants:

dbSNP: 407008
ClinVar: 407008
TCGA: ENSG00000284567
COSMIC: MIR223

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
185550172008MicroRNA-223 is commonly repressed in hepatocellular carcinoma and potentiates expression of Stathmin1.158
216283942011miRNA-223 promotes gastric cancer invasion and metastasis by targeting tumor suppressor EPB41L3.149
229840812012Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1β production.141
179966492007Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein.130
200290462010Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia.129
245769472014HDL-transferred microRNA-223 regulates ICAM-1 expression in endothelial cells.120
229840822012NLRP3 inflammasome activity is negatively controlled by miR-223.113
190476782009Differentiation stage-specific expression of microRNAs in B lymphocytes and diffuse large B-cell lymphomas.105
243077382014Platelet-secreted microRNA-223 promotes endothelial cell apoptosis induced by advanced glycation end products via targeting the insulin-like growth factor 1 receptor.63
284873102017Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome.63

Citation

Dessen P

MIR223 (microRNA 223)

Atlas Genet Cytogenet Oncol Haematol. 2008-07-01

Online version: http://atlasgeneticsoncology.org/gene/50166/mir223-(microrna-223)