CDKN2AIP (CDKN2A interacting protein)

2008-07-01  

Identity

HGNC
LOCATION
4q35.1
LOCUSID
ALIAS
CARF

Other Information

Locus ID:

NCBI: 55602
MIM: 615914
HGNC: 24325
Ensembl: ENSG00000168564

Variants:

dbSNP: 55602
ClinVar: 55602
TCGA: ENSG00000168564
COSMIC: CDKN2AIP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168564ENST00000302350J3KNE1
ENSG00000168564ENST00000504169Q9NXV6
ENSG00000168564ENST00000510928D6RGD2

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
370481422023Fatty Acid Excess Dysregulates CARF to Initiate the Development of Hepatic Steatosis.0
370481422023Fatty Acid Excess Dysregulates CARF to Initiate the Development of Hepatic Steatosis.0
355934752022CDKN2AIP-induced cell senescence and apoptosis of testicular seminoma are associated with CARM1 and eIF4β.1
355934752022CDKN2AIP-induced cell senescence and apoptosis of testicular seminoma are associated with CARM1 and eIF4β.1
322218642020Stress-induced changes in CARF expression determine cell fate to death, survival, or malignant transformation.7
322218642020Stress-induced changes in CARF expression determine cell fate to death, survival, or malignant transformation.7
287545312017CARF is a multi-module regulator of cell proliferation and a molecular bridge between cellular senescence and carcinogenesis.11
287545312017CARF is a multi-module regulator of cell proliferation and a molecular bridge between cellular senescence and carcinogenesis.11
274571282016Loss-of-function screening to identify miRNAs involved in senescence: tumor suppressor activity of miRNA-335 and its new target CARF.8
278292352016CARF activates beta-catenin/TCF signaling in the hepatocellular carcinoma.5
274571282016Loss-of-function screening to identify miRNAs involved in senescence: tumor suppressor activity of miRNA-335 and its new target CARF.8
278292352016CARF activates beta-catenin/TCF signaling in the hepatocellular carcinoma.5
262789982015CARF (Collaborator of ARF) overexpression in p53-deficient cells promotes carcinogenesis.16
265318222015Collaborator of alternative reading frame protein (CARF) regulates early processing of pre-ribosomal RNA by retaining XRN2 (5'-3' exoribonuclease) in the nucleoplasm.15
262789982015CARF (Collaborator of ARF) overexpression in p53-deficient cells promotes carcinogenesis.16

Citation

Dessen P

CDKN2AIP (CDKN2A interacting protein)

Atlas Genet Cytogenet Oncol Haematol. 2008-07-01

Online version: http://atlasgeneticsoncology.org/gene/50210/cdkn2aip