PYDC1 (pyrin domain containing 1)

2008-07-01 Affiliation

Identity

HGNC

PYDC1

LOCATION

16p11.2

LOCUSID

260434

ALIAS

ASC2,POP1,PYC1,cPOP1

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 260434
MIM: 615700
HGNC: 30261
Ensembl: ENSG00000169900

Variants:

dbSNP: 260434
ClinVar: 260434
TCGA: ENSG00000169900
COSMIC: PYDC1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000169900	ENST00000302964	Q8WXC3

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
NOD-like receptor signaling pathway	KEGG	ko04621
NOD-like receptor signaling pathway	KEGG	hsa04621

References

Pubmed ID	Year	Title	Citations
28005267	2017	Human gingiva transcriptome during wound healing.	6
12153040	2002	NMR assignment of human ASC2, a self contained protein interaction domain involved in apoptosis and inflammation.	0
12656673	2003	The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation.	0
16403450	2006	Determining the 3D structure of human ASC2 protein involved in apoptosis and inflammation.	0
16905547	2006	Structure and dynamics of ASC2, a pyrin domain-only protein that regulates inflammatory signaling.	0
23519807	2013	Crystallization and preliminary X-ray crystallographic studies of cPOP1.	0
26510601	2015	[Influence of M680I and M694V mutations on pyrin's domain B30.2 tertiary structure and it's complex formation ability with caspase-1].	0

Citation

Dessen P

PYDC1 (pyrin domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2008-07-01

Online version: http://atlasgeneticsoncology.org/gene/50214/pydc1-(pyrin-domain-containing-1)