Identity
HGNC
LOCATION
18q11.2
LOCUSID
ALIAS
A930014I12Rik,CTF,ECO1,EFO1,ESO1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 114799
MIM: 609674
HGNC: 24645
Ensembl: ENSG00000141446
Variants:
dbSNP: 114799
ClinVar: 114799
TCGA: ENSG00000141446
COSMIC: ESCO1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000141446 | ENST00000269214 | Q5FWF5 |
| ENSG00000141446 | ENST00000269214 | A0A024RC19 |
| ENSG00000141446 | ENST00000383276 | Q5FWF5 |
| ENSG00000141446 | ENST00000622333 | A0A0C4DH04 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Cell Cycle | REACTOME | R-HSA-1640170 |
| Cell Cycle, Mitotic | REACTOME | R-HSA-69278 |
| S Phase | REACTOME | R-HSA-69242 |
| Establishment of Sister Chromatid Cohesion | REACTOME | R-HSA-2468052 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31935221 | 2020 | Non-redundant roles in sister chromatid cohesion of the DNA helicase DDX11 and the SMC3 acetyl transferases ESCO1 and ESCO2. | 13 |
| 32065581 | 2020 | ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesin(STAG1) from WAPL. | 62 |
| 32555289 | 2020 | Alternative catalytic residues in the active site of Esco acetyltransferases. | 2 |
| 31935221 | 2020 | Non-redundant roles in sister chromatid cohesion of the DNA helicase DDX11 and the SMC3 acetyl transferases ESCO1 and ESCO2. | 13 |
| 32065581 | 2020 | ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesin(STAG1) from WAPL. | 62 |
| 32555289 | 2020 | Alternative catalytic residues in the active site of Esco acetyltransferases. | 2 |
| 28847955 | 2017 | Esco1 and Esco2 regulate distinct cohesin functions during cell cycle progression. | 52 |
| 28847955 | 2017 | Esco1 and Esco2 regulate distinct cohesin functions during cell cycle progression. | 52 |
| 26547586 | 2016 | Increased expression of ESCO1 is correlated with poor patient survival and its role in human bladder cancer. | 10 |
| 27803161 | 2016 | Molecular Basis for Cohesin Acetylation by Establishment of Sister Chromatid Cohesion N-Acetyltransferase ESCO1. | 7 |
| 26547586 | 2016 | Increased expression of ESCO1 is correlated with poor patient survival and its role in human bladder cancer. | 10 |
| 27803161 | 2016 | Molecular Basis for Cohesin Acetylation by Establishment of Sister Chromatid Cohesion N-Acetyltransferase ESCO1. | 7 |
| 26051894 | 2015 | Esco1 Acetylates Cohesin via a Mechanism Different from That of Esco2. | 42 |
| 26305936 | 2015 | Cohesin recruits the Esco1 acetyltransferase genome wide to repress transcription and promote cohesion in somatic cells. | 25 |
| 26051894 | 2015 | Esco1 Acetylates Cohesin via a Mechanism Different from That of Esco2. | 42 |
Citation
Dessen P
ESCO1 (establishment of sister chromatid cohesion N-acetyltransferase 1)
Atlas Genet Cytogenet Oncol Haematol. 2008-07-01
Online version: http://atlasgeneticsoncology.org/gene/50238/esco1-(establishment-of-sister-chromatid-cohesion-n-acetyltransferase-1)
