NSMCE1 (NSE1 homolog, SMC5-SMC6 complex component)

2008-07-01  

Identity

HGNC
LOCATION
16p12.1
LOCUSID
ALIAS
NSE1
FUSION GENES

Other Information

Locus ID:

NCBI: 197370
MIM: 617263
HGNC: 29897
Ensembl: ENSG00000169189

Variants:

dbSNP: 197370
ClinVar: 197370
TCGA: ENSG00000169189
COSMIC: NSMCE1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169189ENST00000361439Q8WV22
ENSG00000169189ENST00000562039H3BV05
ENSG00000169189ENST00000563273I3L1I3
ENSG00000169189ENST00000563900H3BSL0
ENSG00000169189ENST00000564342H3BR73
ENSG00000169189ENST00000566087H3BR31
ENSG00000169189ENST00000567710H3BN81
ENSG00000169189ENST00000569236H3BR31

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
SUMOylationREACTOMER-HSA-2990846
SUMO E3 ligases SUMOylate target proteinsREACTOMER-HSA-3108232
SUMOylation of DNA damage response and repair proteinsREACTOMER-HSA-3108214

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
323896902020Molecular Insights into the Architecture of the Human SMC5/6 Complex.16
323896902020Molecular Insights into the Architecture of the Human SMC5/6 Complex.16
186675312008Nse1 RING-like domain supports functions of the Smc5-Smc6 holocomplex in genome stability.40
186675312008Nse1 RING-like domain supports functions of the Smc5-Smc6 holocomplex in genome stability.40

Citation

Dessen P

NSMCE1 (NSE1 homolog, SMC5-SMC6 complex component)

Atlas Genet Cytogenet Oncol Haematol. 2008-07-01

Online version: http://atlasgeneticsoncology.org/gene/50241/js/humanGenome