FCER1G (Fc fragment of IgE receptor Ig)

2008-07-01  

Identity

HGNC
LOCATION
1q23.3
LOCUSID
ALIAS
FCRG
FUSION GENES

Other Information

Locus ID:

NCBI: 2207
MIM: 147139
HGNC: 3611
Ensembl: ENSG00000158869

Variants:

dbSNP: 2207
ClinVar: 2207
TCGA: ENSG00000158869
COSMIC: FCER1G

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000158869ENST00000289902P30273
ENSG00000158869ENST00000367992A6NCQ8

Expression (GTEx)

0
500
1000
1500

Pathways

PathwaySourceExternal ID
Natural killer cell mediated cytotoxicityKEGGko04650
Fc epsilon RI signaling pathwayKEGGko04664
AsthmaKEGGko05310
Natural killer cell mediated cytotoxicityKEGGhsa04650
Fc epsilon RI signaling pathwayKEGGhsa04664
AsthmaKEGGhsa05310
TuberculosisKEGGko05152
TuberculosisKEGGhsa05152
Platelet activationKEGGhsa04611
Sphingolipid signaling pathwayKEGGhsa04071
Sphingolipid signaling pathwayKEGGko04071
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Fc epsilon receptor (FCERI) signalingREACTOMER-HSA-2454202
C-type lectin receptors (CLRs)REACTOMER-HSA-5621481
Dectin-2 familyREACTOMER-HSA-5621480
HemostasisREACTOMER-HSA-109582
Platelet Adhesion to exposed collagenREACTOMER-HSA-75892
Platelet activation, signaling and aggregationREACTOMER-HSA-76002
GPVI-mediated activation cascadeREACTOMER-HSA-114604
Cell surface interactions at the vascular wallREACTOMER-HSA-202733
Phospholipase D signaling pathwayKEGGko04072
Phospholipase D signaling pathwayKEGGhsa04072
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA443450AsthmaDiseaseClinicalAnnotationassociatedPD18534082, 18595682
PA448497aspirinChemicalClinicalAnnotationassociatedPD18534082, 18595682

References

Pubmed IDYearTitleCitations
360548192023Fc Fragment of IgE Receptor Ig (FCER1G) acts as a key gene involved in cancer immune infiltration and tumour microenvironment.9
371707582023Identification of FCER1G as a key gene in multiple myeloma based on weighted gene co-expression network analysis.0
378210742023Identification of FCER1G as a cyclosporin A plus corticosteroid sensitization gene in female patients with Vogt-Koyanagi-Harada disease.0
360548192023Fc Fragment of IgE Receptor Ig (FCER1G) acts as a key gene involved in cancer immune infiltration and tumour microenvironment.9
371707582023Identification of FCER1G as a key gene in multiple myeloma based on weighted gene co-expression network analysis.0
378210742023Identification of FCER1G as a cyclosporin A plus corticosteroid sensitization gene in female patients with Vogt-Koyanagi-Harada disease.0
350784332022The role of SPI1-TYROBP-FCER1G network in oncogenesis and prognosis of osteosarcoma, and its association with immune infiltration.6
360664912022Diminished cell proliferation promotes natural killer cell adaptive-like phenotype by limiting FcεRIγ expression.24
350784332022The role of SPI1-TYROBP-FCER1G network in oncogenesis and prognosis of osteosarcoma, and its association with immune infiltration.6
360664912022Diminished cell proliferation promotes natural killer cell adaptive-like phenotype by limiting FcεRIγ expression.24
337866722021Identification of TYROBP and FCER1G as Key Genes with Prognostic Value in Clear Cell Renal Cell Carcinoma by Bioinformatics Analysis.6
341155262021FCER1G and PTGS2 Serve as Potential Diagnostic Biomarkers of Acute Myocardial Infarction Based on Integrated Bioinformatics Analyses.9
337866722021Identification of TYROBP and FCER1G as Key Genes with Prognostic Value in Clear Cell Renal Cell Carcinoma by Bioinformatics Analysis.6
341155262021FCER1G and PTGS2 Serve as Potential Diagnostic Biomarkers of Acute Myocardial Infarction Based on Integrated Bioinformatics Analyses.9
318670152019Phenotypic and Functional Analysis of Human NK Cell Subpopulations According to the Expression of FcεRIγ and NKG2C.13

Citation

Dessen P

FCER1G (Fc fragment of IgE receptor Ig)

Atlas Genet Cytogenet Oncol Haematol. 2008-07-01

Online version: http://atlasgeneticsoncology.org/gene/50245/fcer1g-(fc-fragment-of-ige-receptor-ig)