DACH1 (dachshund family transcription factor 1)

2008-07-01  

Identity

HGNC
LOCATION
13q21.33
LOCUSID
ALIAS
DACH
FUSION GENES

Other Information

Locus ID:

NCBI: 1602
MIM: 603803
HGNC: 2663
Ensembl: ENSG00000276644

Variants:

dbSNP: 1602
ClinVar: 1602
TCGA: ENSG00000276644
COSMIC: DACH1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000276644ENST00000611519Q9UI36
ENSG00000276644ENST00000613252Q9UI36
ENSG00000276644ENST00000619232Q9UI36
ENSG00000276644ENST00000620444Q9UI36

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203831462010New loci associated with kidney function and chronic kidney disease.337
145639992003Scanning human gene deserts for long-range enhancers.254
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
169806152006DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth.63
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
145259832003DACH1 inhibits transforming growth factor-beta signaling through binding Smad4.50
184674912008Dachshund inhibits oncogene-induced breast cancer cellular migration and invasion through suppression of interleukin-8.47
193518402009The cell fate determination factor dachshund inhibits androgen receptor signaling and prostate cancer cellular growth.41
241493232013Epigenetic regulation of DACH1, a novel Wnt signaling component in colorectal cancer.39
199019652010Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis.36

Citation

Dessen P

DACH1 (dachshund family transcription factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2008-07-01

Online version: http://atlasgeneticsoncology.org/gene/50251/dach1-(dachshund-family-transcription-factor-1)