Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79816
MIM: 612399
HGNC: 30788
Ensembl: ENSG00000104953
Variants:
dbSNP: 79816
ClinVar: 79816
TCGA: ENSG00000104953
COSMIC: TLE6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000104953 | ENST00000246112 | Q9H808 |
| ENSG00000104953 | ENST00000452088 | Q9H808 |
| ENSG00000104953 | ENST00000453329 | C9J532 |
| ENSG00000104953 | ENST00000482627 | K7ENW8 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34036456 | 2021 | Two novel mutations in PADI6 and TLE6 genes cause female infertility due to arrest in embryonic development. | 12 |
| 34264011 | 2021 | A novel TLE6 mutation, c.541+1G>A, identified using whole-exome sequencing in a Chinese family with female infertility. | 5 |
| 34036456 | 2021 | Two novel mutations in PADI6 and TLE6 genes cause female infertility due to arrest in embryonic development. | 12 |
| 34264011 | 2021 | A novel TLE6 mutation, c.541+1G>A, identified using whole-exome sequencing in a Chinese family with female infertility. | 5 |
| 31897846 | 2020 | Expanding the genetic and phenotypic spectrum of female infertility caused by TLE6 mutations. | 21 |
| 31897846 | 2020 | Expanding the genetic and phenotypic spectrum of female infertility caused by TLE6 mutations. | 21 |
| 26537248 | 2015 | TLE6 mutation causes the earliest known human embryonic lethality. | 81 |
| 26537248 | 2015 | TLE6 mutation causes the earliest known human embryonic lethality. | 81 |
| 24356439 | 2013 | Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth. | 39 |
| 24356439 | 2013 | Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth. | 39 |
| 18551179 | 2008 | Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression. | 21 |
| 18551179 | 2008 | Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression. | 21 |
Citation
Dessen P
TLE6 (TLE family member 6, subcortical maternal complex member)
Atlas Genet Cytogenet Oncol Haematol. 2008-08-01
Online version: http://atlasgeneticsoncology.org/gene/50289/tle6-(tle-family-member-6-subcortical-maternal-complex-member)
