Identity
HGNC
LOCATION
12q13.3
LOCUSID
ALIAS
OBFC2B,SOSS-B1,SSB1,hSSB1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79035
MIM: 612104
HGNC: 28412
Ensembl: ENSG00000139579
Variants:
dbSNP: 79035
ClinVar: 79035
TCGA: ENSG00000139579
COSMIC: NABP2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| RNA polymerase II transcribes snRNA genes | REACTOME | R-HSA-6807505 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36811381 | 2023 | hSSB1 (NABP2/OBFC2B) modulates the DNA damage and androgen-induced transcriptional response in prostate cancer. | 5 |
| 36811381 | 2023 | hSSB1 (NABP2/OBFC2B) modulates the DNA damage and androgen-induced transcriptional response in prostate cancer. | 5 |
| 34270706 | 2021 | Genome-wide association study in the Taiwan Biobank identifies four novel genes for human height: NABP2, RASA2, RNF41 and SLC39A5. | 1 |
| 34464898 | 2021 | Mechanisms of SSBP1 variants in mitochondrial disease: Molecular dynamics simulations reveal stable tetramers with altered DNA binding surfaces. | 5 |
| 34270706 | 2021 | Genome-wide association study in the Taiwan Biobank identifies four novel genes for human height: NABP2, RASA2, RNF41 and SLC39A5. | 1 |
| 34464898 | 2021 | Mechanisms of SSBP1 variants in mitochondrial disease: Molecular dynamics simulations reveal stable tetramers with altered DNA binding surfaces. | 5 |
| 28506294 | 2017 | hSSB1 associates with and promotes stability of the BLM helicase. | 5 |
| 28506294 | 2017 | hSSB1 associates with and promotes stability of the BLM helicase. | 5 |
| 27273218 | 2016 | hSSB1 (NABP2/OBFC2B) is regulated by oxidative stress. | 18 |
| 27387285 | 2016 | A structural analysis of DNA binding by hSSB1 (NABP2/OBFC2B) in solution. | 15 |
| 27273218 | 2016 | hSSB1 (NABP2/OBFC2B) is regulated by oxidative stress. | 18 |
| 27387285 | 2016 | A structural analysis of DNA binding by hSSB1 (NABP2/OBFC2B) in solution. | 15 |
| 26261212 | 2015 | hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway. | 19 |
| 26261212 | 2015 | hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway. | 19 |
| 24753408 | 2014 | Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks. | 33 |
Citation
Dessen P
NABP2 (nucleic acid binding protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2008-08-01
Online version: http://atlasgeneticsoncology.org/gene/50299/nabp2-(nucleic-acid-binding-protein-2)
