Identity
HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
C16orf8,Dist1,EGFR-RS,gene-89,gene-90,hDist1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64285
MIM: 614403
HGNC: 20561
Ensembl: ENSG00000007384
Variants:
dbSNP: 64285
ClinVar: 64285
TCGA: ENSG00000007384
COSMIC: RHBDF1
RNA/Proteins
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37979663 | 2023 | RHBDF1 deficiency suppresses melanoma glycolysis and enhances efficacy of immunotherapy by facilitating glucose-6-phosphate isomerase degradation via TRIM32. | 0 |
| 37979663 | 2023 | RHBDF1 deficiency suppresses melanoma glycolysis and enhances efficacy of immunotherapy by facilitating glucose-6-phosphate isomerase degradation via TRIM32. | 0 |
| 35585977 | 2022 | Attenuation of Excess TNF-α Release in Crohn's Disease by Silencing of iRHOMs 1/2 and the Restoration of TGF-β Mediated Immunosuppression Through Modulation of TACE Trafficking. | 3 |
| 35595096 | 2022 | Alternative splicing of the human rhomboid family-1 gene RHBDF1 inhibits epidermal growth factor receptor activation. | 2 |
| 35585977 | 2022 | Attenuation of Excess TNF-α Release in Crohn's Disease by Silencing of iRHOMs 1/2 and the Restoration of TGF-β Mediated Immunosuppression Through Modulation of TACE Trafficking. | 3 |
| 35595096 | 2022 | Alternative splicing of the human rhomboid family-1 gene RHBDF1 inhibits epidermal growth factor receptor activation. | 2 |
| 34276048 | 2021 | RHBDF1 promotes AP-1-activated endothelial-mesenchymal transition in tumor fibrotic stroma formation. | 4 |
| 34276048 | 2021 | RHBDF1 promotes AP-1-activated endothelial-mesenchymal transition in tumor fibrotic stroma formation. | 4 |
| 31661139 | 2020 | Association of iRhom1 and iRhom2 expression with prognosis in patients with cervical cancer and possible signaling pathways. | 13 |
| 31661139 | 2020 | Association of iRhom1 and iRhom2 expression with prognosis in patients with cervical cancer and possible signaling pathways. | 13 |
| 29654741 | 2018 | RHBDF1 regulates APC-mediated stimulation of the epithelial-to-mesenchymal transition and proliferation of colorectal cancer cells in part via the Wnt/β-catenin signalling pathway. | 11 |
| 29727209 | 2018 | Perturbation of epithelial apicobasal polarity by rhomboid family-1 gene overexpression. | 6 |
| 30279141 | 2018 | Human rhomboid family-1 modulates clathrin coated vesicle-dependent pro-transforming growth factor α membrane trafficking to promote breast cancer progression. | 8 |
| 29654741 | 2018 | RHBDF1 regulates APC-mediated stimulation of the epithelial-to-mesenchymal transition and proliferation of colorectal cancer cells in part via the Wnt/β-catenin signalling pathway. | 11 |
| 29727209 | 2018 | Perturbation of epithelial apicobasal polarity by rhomboid family-1 gene overexpression. | 6 |
Citation
Dessen P
RHBDF1 (rhomboid 5 homolog 1)
Atlas Genet Cytogenet Oncol Haematol. 2008-09-01
Online version: http://atlasgeneticsoncology.org/gene/50317/rhbdf1
