Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2166
MIM: 602935
HGNC: 3553
Ensembl: ENSG00000117480
Variants:
dbSNP: 2166
ClinVar: 2166
TCGA: ENSG00000117480
COSMIC: FAAH
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000117480 | ENST00000243167 | O00519 |
| ENSG00000117480 | ENST00000484697 | A0A087WYA0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10026 | aripiprazole | Chemical | ClinicalAnnotation | associated | PD | 20631561 | |
| PA131890620 | cannabinoids | Chemical | ClinicalAnnotation | associated | PD | 17290447 | |
| PA444702 | Kyphosis | Disease | VariantAnnotation | associated | PD | ||
| PA445522 | Respiratory Insufficiency | Disease | VariantAnnotation | ambiguous | PD | ||
| PA445619 | Scoliosis | Disease | VariantAnnotation | associated | PD | ||
| PA446876 | Substance-Related Disorders | Disease | ClinicalAnnotation | associated | PD | 17290447, 23556448, 31789429 | |
| PA446970 | Postoperative Nausea and Vomiting | Disease | VariantAnnotation | not associated | PD | ||
| PA447215 | Psychotic Disorders | Disease | ClinicalAnnotation | associated | PD | 20631561 | |
| PA449061 | clozapine | Chemical | ClinicalAnnotation | associated | PD | 20631561 | |
| PA449841 | haloperidol | Chemical | ClinicalAnnotation | associated | PD | 20631561 | |
| PA449957 | ibuprofen | Chemical | Pathway | associated | 25502615 | ||
| PA450403 | methamphetamine | Chemical | ClinicalAnnotation | associated | PD | 23556448, 31789429 | |
| PA450550 | morphine | Chemical | ClinicalAnnotation, VariantAnnotation | ambiguous | PD | ||
| PA450688 | olanzapine | Chemical | ClinicalAnnotation | associated | PD | 20631561 | |
| PA451201 | quetiapine | Chemical | ClinicalAnnotation | associated | PD | 20631561 | |
| PA451257 | risperidone | Chemical | ClinicalAnnotation | associated | PD | 20631561 | |
| PA452618 | opioids | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38114812 | 2024 | Association between the FAAH C385A variant (rs324420) and obesity-related traits: a systematic review. | 0 |
| 38114812 | 2024 | Association between the FAAH C385A variant (rs324420) and obesity-related traits: a systematic review. | 0 |
| 34171108 | 2023 | Cannabinoid receptor type 2 gene is associated with comorbidity of schizophrenia and cannabis dependence and fatty acid amide hydrolase gene is associated with cannabis dependence in the Spanish population. | 6 |
| 35900294 | 2023 | Fatty Acid Amide Hydrolase: An Integrative Clinical Perspective. | 3 |
| 36300805 | 2023 | Fatty acid amide hydrolase C385A polymorphism affects susceptibility to various diseases. | 2 |
| 36372184 | 2023 | Endocannabinoid hydrolases differentially distribute in platelets and red blood cells and are differentially released by thrombin. | 1 |
| 36868890 | 2023 | Association Between Fatty Acid Amide Hydrolase and Alcohol Response Phenotypes: A Positron Emission Tomography Imaging Study With [(11)C]CURB in Heavy-Drinking Youth. | 3 |
| 37018974 | 2023 | The study of rs324420 (C385A) polymorphism of the FAAH gene of the endocannabinoid system in patients with epilepsy and ADHD. | 1 |
| 37253733 | 2023 | Identification of fatty acid amide hydrolase as a metastasis suppressor in breast cancer. | 2 |
| 37372343 | 2023 | Association of FAAH rs324420 (C385A) Polymorphism with High-Level Performance in Volleyball Players. | 2 |
| 37433211 | 2023 | FAAH Pro129Thr Variant Is Associated with Increased Cholesterol Levels in Normal-Weight Metabolically Unhealthy Subjects. | 0 |
| 37761966 | 2023 | Functional Variation in the FAAH Gene Is Directly Associated with Subjective Well-Being and Indirectly Associated with Problematic Alcohol Use. | 2 |
| 34171108 | 2023 | Cannabinoid receptor type 2 gene is associated with comorbidity of schizophrenia and cannabis dependence and fatty acid amide hydrolase gene is associated with cannabis dependence in the Spanish population. | 6 |
| 35900294 | 2023 | Fatty Acid Amide Hydrolase: An Integrative Clinical Perspective. | 3 |
| 36300805 | 2023 | Fatty acid amide hydrolase C385A polymorphism affects susceptibility to various diseases. | 2 |
Citation
Dessen P
FAAH (fatty acid amide hydrolase)
Atlas Genet Cytogenet Oncol Haematol. 2008-09-01
Online version: http://atlasgeneticsoncology.org/gene/50330/faah-(fatty-acid-amide-hydrolase)
