ZKSCAN3 (zinc finger with KRAB and SCAN domains 3)

2008-09-01  

Identity

HGNC
ZKSCAN3
LOCATION
6p22.1
LOCUSID
80317
ALIAS
ZF47,ZFP306,ZNF306,ZNF309,ZSCAN13,ZSCAN35,Zfp47,dJ874C20.1,dJ874C20.1.,zfp-47
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 80317
MIM: 612791
HGNC: 13853
Ensembl: ENSG00000189298

Variants:

dbSNP: 80317
ClinVar: 80317
TCGA: ENSG00000189298
COSMIC: ZKSCAN3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000189298ENST00000252211Q9BRR0
ENSG00000189298ENST00000341464Q9BRR0
ENSG00000189298ENST00000377255Q9BRR0

Expression (GTEx)

0
1
2
3
4
5
6
7
8
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
386715502024Expression of ZKSCAN3 protein suppresses proliferation, migration, and invasion of pancreatic cancer through autophagy.1
386715502024Expression of ZKSCAN3 protein suppresses proliferation, migration, and invasion of pancreatic cancer through autophagy.1
371754932023Effect of Lacking ZKSCAN3 on Autophagy, Lysosomal Biogenesis and Senescence.0
371754932023Effect of Lacking ZKSCAN3 on Autophagy, Lysosomal Biogenesis and Senescence.0
357796342022Context-dependent pro- and anti-resection roles of ZKSCAN3 in the regulation of fork processing during replication stress.1
357796342022Context-dependent pro- and anti-resection roles of ZKSCAN3 in the regulation of fork processing during replication stress.1
346547972021CHD1L augments autophagy-mediated migration of hepatocellular carcinoma through targeting ZKSCAN3.12
346854842021Role of the Transcriptional Repressor Zinc Finger with KRAB and SCAN Domains 3 (ZKSCAN3) in Retinal Pigment Epithelial Cells.2
346547972021CHD1L augments autophagy-mediated migration of hepatocellular carcinoma through targeting ZKSCAN3.12
346854842021Role of the Transcriptional Repressor Zinc Finger with KRAB and SCAN Domains 3 (ZKSCAN3) in Retinal Pigment Epithelial Cells.2
318925552020Prognostic Significance of ZKSCAN3 (ZNF306) Expression in Gastric Carcinoma.6
324273302020ZKSCAN3 counteracts cellular senescence by stabilizing heterochromatin.44
325419272020Human ZKSCAN3 and Drosophila M1BP are functionally homologous transcription factors in autophagy regulation.10
318925552020Prognostic Significance of ZKSCAN3 (ZNF306) Expression in Gastric Carcinoma.6
324273302020ZKSCAN3 counteracts cellular senescence by stabilizing heterochromatin.44

Citation

Dessen P

ZKSCAN3 (zinc finger with KRAB and SCAN domains 3)

Atlas Genet Cytogenet Oncol Haematol. 2008-09-01

Online version: http://atlasgeneticsoncology.org/gene/50355/zkscan3-(zinc-finger-with-krab-and-scan-domains-3)