Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26272
MIM: 609090
HGNC: 13583
Ensembl: ENSG00000151876
Variants:
dbSNP: 26272
ClinVar: 26272
TCGA: ENSG00000151876
COSMIC: FBXO4
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33784509 | 2021 | FBX4 mediates rapid cyclin D1 proteolysis upon DNA damage in immortalized esophageal epithelial cells. | 2 |
| 33784509 | 2021 | FBX4 mediates rapid cyclin D1 proteolysis upon DNA damage in immortalized esophageal epithelial cells. | 2 |
| 28776569 | 2017 | FBXO4 inhibits lung cancer cell survival by targeting Mcl-1 for degradation. | 13 |
| 29142209 | 2017 | Fbxo4-mediated degradation of Fxr1 suppresses tumorigenesis in head and neck squamous cell carcinoma. | 31 |
| 28776569 | 2017 | FBXO4 inhibits lung cancer cell survival by targeting Mcl-1 for degradation. | 13 |
| 29142209 | 2017 | Fbxo4-mediated degradation of Fxr1 suppresses tumorigenesis in head and neck squamous cell carcinoma. | 31 |
| 24704453 | 2014 | Alternative splicing variants of human Fbx4 disturb cyclin D1 proteolysis in human cancer. | 10 |
| 24704453 | 2014 | Alternative splicing variants of human Fbx4 disturb cyclin D1 proteolysis in human cancer. | 10 |
| 24019069 | 2013 | The FBXO4 tumor suppressor functions as a barrier to BRAFV600E-dependent metastatic melanoma. | 20 |
| 24019069 | 2013 | The FBXO4 tumor suppressor functions as a barrier to BRAFV600E-dependent metastatic melanoma. | 20 |
| 21242966 | 2011 | Phosphorylation-dependent regulation of SCF(Fbx4) dimerization and activity involves a novel component, 14-3-3ɛ. | 23 |
| 21242966 | 2011 | Phosphorylation-dependent regulation of SCF(Fbx4) dimerization and activity involves a novel component, 14-3-3ɛ. | 23 |
| 20159592 | 2010 | Structural basis of selective ubiquitination of TRF1 by SCFFbx4. | 31 |
| 20181953 | 2010 | Structural basis of dimerization-dependent ubiquitination by the SCF(Fbx4) ubiquitin ligase. | 20 |
| 20159592 | 2010 | Structural basis of selective ubiquitination of TRF1 by SCFFbx4. | 31 |
Citation
Dessen P
FBXO4 (F-box protein 4)
Atlas Genet Cytogenet Oncol Haematol. 2008-09-01
Online version: http://atlasgeneticsoncology.org/gene/50376/fbxo4-(f-box-protein-4)
