Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 333
MIM: 104775
HGNC: 597
Ensembl: ENSG00000105290
Variants:
dbSNP: 333
ClinVar: 333
TCGA: ENSG00000105290
COSMIC: APLP1
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38821932 | 2024 | Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein. | 0 |
| 38821932 | 2024 | Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein. | 0 |
| 29382944 | 2018 | APLP1 is endoproteolytically cleaved by γ-secretase without previous ectodomain shedding. | 14 |
| 29382944 | 2018 | APLP1 is endoproteolytically cleaved by γ-secretase without previous ectodomain shedding. | 14 |
| 28987665 | 2017 | Altered spontaneous brain activity pattern in cognitively normal young adults carrying mutations of APP, presenilin-1/2 and APOE ε4. | 2 |
| 29021345 | 2017 | Direct evidence of amyloid precursor-like protein 1 trans interactions in cell-cell adhesion platforms investigated via fluorescence fluctuation spectroscopy. | 17 |
| 28987665 | 2017 | Altered spontaneous brain activity pattern in cognitively normal young adults carrying mutations of APP, presenilin-1/2 and APOE ε4. | 2 |
| 29021345 | 2017 | Direct evidence of amyloid precursor-like protein 1 trans interactions in cell-cell adhesion platforms investigated via fluorescence fluctuation spectroscopy. | 17 |
| 25683482 | 2015 | APLP1 and APLP2, members of the APP family of proteins, behave similarly to APP in that they associate with NMDA receptors and enhance NMDA receptor surface expression. | 20 |
| 25760599 | 2015 | Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes. | 5 |
| 25683482 | 2015 | APLP1 and APLP2, members of the APP family of proteins, behave similarly to APP in that they associate with NMDA receptors and enhance NMDA receptor surface expression. | 20 |
| 25760599 | 2015 | Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes. | 5 |
| 24740518 | 2014 | Altered cerebrospinal fluid levels of amyloid β and amyloid precursor-like protein 1 peptides in Down's syndrome. | 14 |
| 24740518 | 2014 | Altered cerebrospinal fluid levels of amyloid β and amyloid precursor-like protein 1 peptides in Down's syndrome. | 14 |
| 23874953 | 2013 | Turnover of amyloid precursor protein family members determines their nuclear signaling capability. | 18 |
Citation
Dessen P
APLP1 (amyloid beta precursor like protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2008-09-01
Online version: http://atlasgeneticsoncology.org/gene/50382/aplp1-(amyloid-beta-precursor-like-protein-1)
