Identity
HGNC
LOCATION
19q13.2
LOCUSID
ALIAS
RRP41B,RRP46,Rrp46p,hRrp46p,p12B
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 56915
MIM: 606492
HGNC: 24662
Ensembl: ENSG00000077348
Variants:
dbSNP: 56915
ClinVar: 56915
TCGA: ENSG00000077348
COSMIC: EXOSC5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000077348 | ENST00000221233 | Q9NQT4 |
| ENSG00000077348 | ENST00000593771 | M0R102 |
| ENSG00000077348 | ENST00000596905 | M0R050 |
| ENSG00000077348 | ENST00000602129 | M0R289 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34089229 | 2021 | Risk of sudden cardiac death in EXOSC5-related disease. | 6 |
| 34089229 | 2021 | Risk of sudden cardiac death in EXOSC5-related disease. | 6 |
| 32504085 | 2020 | Biallelic variants in the RNA exosome gene EXOSC5 are associated with developmental delays, short stature, cerebellar hypoplasia and motor weakness. | 15 |
| 32504085 | 2020 | Biallelic variants in the RNA exosome gene EXOSC5 are associated with developmental delays, short stature, cerebellar hypoplasia and motor weakness. | 15 |
| 30567989 | 2019 | Peroxiredoxin 1, a Novel HBx-Interacting Protein, Interacts with Exosome Component 5 and Negatively Regulates Hepatitis B Virus (HBV) Propagation through Degradation of HBV RNA. | 21 |
| 30567989 | 2019 | Peroxiredoxin 1, a Novel HBx-Interacting Protein, Interacts with Exosome Component 5 and Negatively Regulates Hepatitis B Virus (HBV) Propagation through Degradation of HBV RNA. | 21 |
| 23392705 | 2013 | Interaction of human genes WT1 and CML28 in leukemic cells. | 0 |
| 23392705 | 2013 | Interaction of human genes WT1 and CML28 in leukemic cells. | 0 |
| 20660080 | 2010 | Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation. | 8 |
| 20660080 | 2010 | Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation. | 8 |
| 18157497 | 2008 | Activation of cytotoxic T lymphocytes against CML28-bearing tumors by dendritic cells transduced with a recombinant adeno-associated virus encoding the CML28 gene. | 7 |
| 18157497 | 2008 | Activation of cytotoxic T lymphocytes against CML28-bearing tumors by dendritic cells transduced with a recombinant adeno-associated virus encoding the CML28 gene. | 7 |
| 16815301 | 2006 | Induction of CML28-specific cytotoxic T cell responses using co-transfected dendritic cells with CML28 DNA vaccine and SOCS1 small interfering RNA expression vector. | 5 |
| 16815301 | 2006 | Induction of CML28-specific cytotoxic T cell responses using co-transfected dendritic cells with CML28 DNA vaccine and SOCS1 small interfering RNA expression vector. | 5 |
| 11812149 | 2002 | Protein-protein interactions of hCsl4p with other human exosome subunits. | 10 |
Citation
Dessen P
EXOSC5 (exosome component 5)
Atlas Genet Cytogenet Oncol Haematol. 2008-09-01
Online version: http://atlasgeneticsoncology.org/gene/50386/exosc5-(exosome-component-5)
