Identity
HGNC
LOCATION
17p13.2
LOCUSID
ALIAS
COXPD33,GC1QBP,HABP1,SF2AP32,SF2p32,gC1Q-R,gC1qR,p32
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 708
MIM: 601269
HGNC: 1243
Ensembl: ENSG00000108561
Variants:
dbSNP: 708
ClinVar: 708
TCGA: ENSG00000108561
COSMIC: C1QBP
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000108561 | ENST00000225698 | Q07021 |
| ENSG00000108561 | ENST00000570805 | I3L3Q7 |
| ENSG00000108561 | ENST00000574444 | I3L3B0 |
| ENSG00000108561 | ENST00000576122 | A0A0G2JLC0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38395904 | 2024 | Genetic and pharmacologic p32-inhibition rescue CHCHD2-linked Parkinson's disease phenotypes in vivo and in cell models. | 1 |
| 38473963 | 2024 | Inhibition of Multifunctional Protein p32/C1QBP Promotes Cytostatic Effects in Colon Cancer Cells by Altering Mitogenic Signaling Pathways and Promoting Mitochondrial Damage. | 0 |
| 38395904 | 2024 | Genetic and pharmacologic p32-inhibition rescue CHCHD2-linked Parkinson's disease phenotypes in vivo and in cell models. | 1 |
| 38473963 | 2024 | Inhibition of Multifunctional Protein p32/C1QBP Promotes Cytostatic Effects in Colon Cancer Cells by Altering Mitogenic Signaling Pathways and Promoting Mitochondrial Damage. | 0 |
| 36674861 | 2023 | C1QBP Mediates Breast Cancer Cell Proliferation and Growth via Multiple Potential Signalling Pathways. | 2 |
| 36705413 | 2023 | Complement component C1q initiates extrinsic coagulation via the receptor for the globular head of C1q in adventitial fibroblasts and vascular smooth muscle cells. | 2 |
| 36674861 | 2023 | C1QBP Mediates Breast Cancer Cell Proliferation and Growth via Multiple Potential Signalling Pathways. | 2 |
| 36705413 | 2023 | Complement component C1q initiates extrinsic coagulation via the receptor for the globular head of C1q in adventitial fibroblasts and vascular smooth muscle cells. | 2 |
| 34494203 | 2022 | gC1qR Antibody Can Modulate Endothelial Cell Permeability in Angioedema. | 3 |
| 35128841 | 2022 | Identification of Mitofusin 1 and Complement Component 1q Subcomponent Binding Protein as Mitochondrial Targets in Systemic Lupus Erythematosus. | 6 |
| 34494203 | 2022 | gC1qR Antibody Can Modulate Endothelial Cell Permeability in Angioedema. | 3 |
| 35128841 | 2022 | Identification of Mitofusin 1 and Complement Component 1q Subcomponent Binding Protein as Mitochondrial Targets in Systemic Lupus Erythematosus. | 6 |
| 33515804 | 2021 | Loss of Mucosal p32/gC1qR/HABP1 Triggers Energy Deficiency and Impairs Goblet Cell Differentiation in Ulcerative Colitis. | 17 |
| 34003581 | 2021 | Mitochondrial cardiomyopathy and ventricular arrhythmias associated with biallelic variants in C1QBP. | 0 |
| 33515804 | 2021 | Loss of Mucosal p32/gC1qR/HABP1 Triggers Energy Deficiency and Impairs Goblet Cell Differentiation in Ulcerative Colitis. | 17 |
Citation
Dessen P
C1QBP (complement C1q binding protein)
Atlas Genet Cytogenet Oncol Haematol. 2008-10-01
Online version: http://atlasgeneticsoncology.org/gene/50394/c1qbp-(complement-c1q-binding-protein)
