Identity
HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
IIAE6,MyD88-3,PRVTIRB,TICAM-1,TRIF
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 148022
MIM: 607601
HGNC: 18348
Ensembl: ENSG00000127666
Variants:
dbSNP: 148022
ClinVar: 148022
TCGA: ENSG00000127666
COSMIC: TICAM1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000127666 | ENST00000248244 | Q8IUC6 |
| ENSG00000127666 | ENST00000621756 | A0A087WVI8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36978183 | 2023 | Bacterial vesicles block viral replication in macrophages via TLR4-TRIF-axis. | 8 |
| 37668025 | 2023 | [Association of gene polymorphisms of MyD88 and TICAM1 and their interactions with community-acquired pneumonia in children]. | 0 |
| 36978183 | 2023 | Bacterial vesicles block viral replication in macrophages via TLR4-TRIF-axis. | 8 |
| 37668025 | 2023 | [Association of gene polymorphisms of MyD88 and TICAM1 and their interactions with community-acquired pneumonia in children]. | 0 |
| 35812397 | 2022 | Pathogenic Leptospires Limit Dendritic Cell Activation Through Avoidance of TLR4 and TRIF Signaling. | 3 |
| 35812397 | 2022 | Pathogenic Leptospires Limit Dendritic Cell Activation Through Avoidance of TLR4 and TRIF Signaling. | 3 |
| 33057840 | 2021 | TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling. | 348 |
| 34956174 | 2021 | MicroRNA-181b-2 and MicroRNA-21-1 Negatively Regulate NF-κB and IRF3-Mediated Innate Immune Responses via Targeting TRIF in Teleost. | 2 |
| 33057840 | 2021 | TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling. | 348 |
| 34956174 | 2021 | MicroRNA-181b-2 and MicroRNA-21-1 Negatively Regulate NF-κB and IRF3-Mediated Innate Immune Responses via Targeting TRIF in Teleost. | 2 |
| 31818880 | 2020 | Priming Phosphorylation of TANK-Binding Kinase 1 by IκB Kinase β Is Essential in Toll-Like Receptor 3/4 Signaling. | 7 |
| 32221312 | 2020 | New insights in acetaminophen toxicity: HMGB1 contributes by itself to amplify hepatocyte necrosis in vitro through the TLR4-TRIF-RIPK3 axis. | 13 |
| 32243044 | 2020 | Correlation between TICAM1 gene polymorphisms and community-acquired pneumonia in children. | 2 |
| 32394426 | 2020 | Evolutionary model of protein secondary structure capable of revealing new biological relationships. | 1 |
| 32529819 | 2020 | TIR-domain-containing adapter-inducing interferon-β contributes to TLR3/TLR4 triggered apoptosis and inflammation in nucleus pulposus cells. | 0 |
Citation
Dessen P
TICAM1 (toll like receptor adaptor molecule 1)
Atlas Genet Cytogenet Oncol Haematol. 2008-10-01
Online version: http://atlasgeneticsoncology.org/gene/50439/ticam1
