ADAP1 (ArfGAP with dual PH domains 1)

2008-10-01  

Identity

HGNC
LOCATION
7p22.3
LOCUSID
ALIAS
CENTA1,GCS1L,p42IP4
FUSION GENES

Other Information

Locus ID:

NCBI: 11033
MIM: 608114
HGNC: 16486
Ensembl: ENSG00000105963

Variants:

dbSNP: 11033
ClinVar: 11033
TCGA: ENSG00000105963
COSMIC: ADAP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105963ENST00000265846O75689
ENSG00000105963ENST00000435943C9JN36
ENSG00000105963ENST00000437486H7C264
ENSG00000105963ENST00000446141H0Y7Q1
ENSG00000105963ENST00000449296O75689
ENSG00000105963ENST00000453175H7C324
ENSG00000105963ENST00000453823H7C4B3
ENSG00000105963ENST00000454383H7BZT6
ENSG00000105963ENST00000539900O75689
ENSG00000105963ENST00000611167O75689
ENSG00000105963ENST00000617043A0A087WTN6
ENSG00000105963ENST00000649206A0A3B3ISA7

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
386826962024Arf GTPase-Activating proteins ADAP1 and ARAP1 regulate incorporation of CD63 in multivesicular bodies.0
386826962024Arf GTPase-Activating proteins ADAP1 and ARAP1 regulate incorporation of CD63 in multivesicular bodies.0
357028222023Oncogenic fusion transcript analysis identified ADAP1-NOC4L, potentially associated with metastatic colorectal cancer.1
371569992023Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries.28
357028222023Oncogenic fusion transcript analysis identified ADAP1-NOC4L, potentially associated with metastatic colorectal cancer.1
371569992023Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries.28
352329972022ADAP1 promotes latent HIV-1 reactivation by selectively tuning KRAS-ERK-AP-1 T cell signaling-transcriptional axis.2
352329972022ADAP1 promotes latent HIV-1 reactivation by selectively tuning KRAS-ERK-AP-1 T cell signaling-transcriptional axis.2
334431532021In vitro reconstitution reveals phosphoinositides as cargo-release factors and activators of the ARF6 GAP ADAP1.4
334431532021In vitro reconstitution reveals phosphoinositides as cargo-release factors and activators of the ARF6 GAP ADAP1.4
317920622019ADAP1 promotes invasive squamous cell carcinoma progression and predicts patient survival.5
317920622019ADAP1 promotes invasive squamous cell carcinoma progression and predicts patient survival.5
296590662018A mass spectrometry based predictive strategy reveals ADAP1 is phosphorylated at tyrosine 364.1
296590662018A mass spectrometry based predictive strategy reveals ADAP1 is phosphorylated at tyrosine 364.1
248545352014Functions of the neuron-specific protein ADAP1 (centaurin-α1) in neuronal differentiation and neurodegenerative diseases, with an overview of structural and biochemical properties of ADAP1.14

Citation

Dessen P

ADAP1 (ArfGAP with dual PH domains 1)

Atlas Genet Cytogenet Oncol Haematol. 2008-10-01

Online version: http://atlasgeneticsoncology.org/gene/50453/adap1-(arfgap-with-dual-ph-domains-1)