AQP5 (aquaporin 5)

2008-10-01  

Identity

HGNC
LOCATION
12q13.12
LOCUSID
ALIAS
AQP-5,PPKB

Other Information

Locus ID:

NCBI: 362
MIM: 600442
HGNC: 638
Ensembl: ENSG00000161798

Variants:

dbSNP: 362
ClinVar: 362
TCGA: ENSG00000161798
COSMIC: AQP5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000161798ENST00000293599P55064

Expression (GTEx)

0
100
200
300
400
500
600

Pathways

PathwaySourceExternal ID
Salivary secretionKEGGko04970
Salivary secretionKEGGhsa04970
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Aquaporin-mediated transportREACTOMER-HSA-445717
Passive transport by AquaporinsREACTOMER-HSA-432047

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
187687912008High-resolution x-ray structure of human aquaporin 5.77
221450492011Aquaporin-5: a marker protein for proliferation and migration of human breast cancer cells.41
185833212008Role of human aquaporin 5 in colorectal carcinogenesis.39
184780762008Expression of aquaporin 5 (AQP5) promotes tumor invasion in human non small cell lung cancer.36
183051622008Shear stress regulates aquaporin-5 and airway epithelial barrier function.32
201066322010Expression profile of multiple aquaporins in human gastric carcinoma and its clinical significance.27
165373792006Transient receptor potential vanilloid 4 regulates aquaporin-5 abundance under hypotonic conditions.24
242241602013Prognostic value of combined aquaporin 3 and aquaporin 5 overexpression in hepatocellular carcinoma.22
265691062015Plasma Membrane Abundance of Human Aquaporin 5 Is Dynamically Regulated by Multiple Pathways.21
176404792007Decreased expression of human aquaporin-5 correlated with mucus overproduction in airways of chronic obstructive pulmonary disease.19

Citation

Dessen P

AQP5 (aquaporin 5)

Atlas Genet Cytogenet Oncol Haematol. 2008-10-01

Online version: http://atlasgeneticsoncology.org/gene/50455/aqp5-(aquaporin-5)