PNCK (pregnancy up-regulated nonubiquitous CaM kinase)

2008-12-01 Affiliation

Identity

HGNC

PNCK

LOCATION

Xq28

LOCUSID

139728

ALIAS

BSTK3,CaMK1b

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 139728
MIM: 300680
HGNC: 13415
Ensembl: ENSG00000130822

Variants:

dbSNP: 139728
ClinVar: 139728
TCGA: ENSG00000130822
COSMIC: PNCK

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000130822	ENST00000340888	Q6P2M8
ENSG00000130822	ENST00000370142	Q6P2M8
ENSG00000130822	ENST00000370145	Q6P2M8
ENSG00000130822	ENST00000370150	Q6P2M8
ENSG00000130822	ENST00000411968	F8WBU7
ENSG00000130822	ENST00000418241	C9J8P0
ENSG00000130822	ENST00000419804	C9J2B9
ENSG00000130822	ENST00000422811	C9JB09
ENSG00000130822	ENST00000423545	C9J2B9
ENSG00000130822	ENST00000425526	C9J2B9
ENSG00000130822	ENST00000433470	F8WAQ5
ENSG00000130822	ENST00000434652	C9JEC5
ENSG00000130822	ENST00000438984	H7BZQ5
ENSG00000130822	ENST00000439087	C9JJ18
ENSG00000130822	ENST00000447676	Q6P2M8
ENSG00000130822	ENST00000458354	C9J2B9

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
33099476	2020	Expression of Pregnancy Up-regulated Non-ubiquitous Calmodulin Kinase (PNCK) in Hepatocellular Carcinoma.	11
33099476	2020	Expression of Pregnancy Up-regulated Non-ubiquitous Calmodulin Kinase (PNCK) in Hepatocellular Carcinoma.	11
25773930	2015	Pnck overexpression in HER-2 gene-amplified breast cancer causes Trastuzumab resistance through a paradoxical PTEN-mediated process.	0
25773930	2015	Pnck overexpression in HER-2 gene-amplified breast cancer causes Trastuzumab resistance through a paradoxical PTEN-mediated process.	0
23634203	2013	Increased expression of pregnancy up-regulated non-ubiquitous calmodulin kinase is associated with poor prognosis in clear cell renal cell carcinoma.	14
23634203	2013	Increased expression of pregnancy up-regulated non-ubiquitous calmodulin kinase is associated with poor prognosis in clear cell renal cell carcinoma.	14
21325639	2011	Pnck induces ligand-independent EGFR degradation by probable perturbation of the Hsp90 chaperone complex.	15
21325639	2011	Pnck induces ligand-independent EGFR degradation by probable perturbation of the Hsp90 chaperone complex.	15
18562482	2008	Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation.	10
18562482	2008	Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation.	10

Citation

Dessen P

PNCK (pregnancy up-regulated nonubiquitous CaM kinase)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50469/pnck-(pregnancy-up-regulated-nonubiquitous-cam-kinase)