Identity
HGNC
LOCATION
5q33.2
LOCUSID
ALIAS
GLUH1,GLUR1,GLURA,GluA1,HBGR1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2890
MIM: 138248
HGNC: 4571
Ensembl: ENSG00000155511
Variants:
dbSNP: 2890
ClinVar: 2890
TCGA: ENSG00000155511
COSMIC: GRIA1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA446155 | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Disease | ClinicalAnnotation | associated | PD | 20592726 | |
| PA448492 | asparaginase | Chemical | ClinicalAnnotation | associated | PD | 20592726 | |
| PA449841 | haloperidol | Chemical | MultilinkAnnotation | associated | 27023437 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36608782 | 2023 | Timely insertion of AMPA receptor in developing vestibular circuits is required for manifestation of righting reflexes and effective navigation. | 1 |
| 36608782 | 2023 | Timely insertion of AMPA receptor in developing vestibular circuits is required for manifestation of righting reflexes and effective navigation. | 1 |
| 34937502 | 2022 | MicroRNA miR-18a-3p promotes osteoporosis and possibly contributes to spinal fracture by inhibiting the glutamate AMPA receptor subunit 1 gene (GRIA1). | 3 |
| 35675825 | 2022 | Identification and functional evaluation of GRIA1 missense and truncation variants in individuals with ID: An emerging neurodevelopmental syndrome. | 10 |
| 34937502 | 2022 | MicroRNA miR-18a-3p promotes osteoporosis and possibly contributes to spinal fracture by inhibiting the glutamate AMPA receptor subunit 1 gene (GRIA1). | 3 |
| 35675825 | 2022 | Identification and functional evaluation of GRIA1 missense and truncation variants in individuals with ID: An emerging neurodevelopmental syndrome. | 10 |
| 32767928 | 2021 | The Identification of Three Key Genes Related to Stemness in Thyroid Carcinoma through Comprehensive Analysis. | 2 |
| 33188547 | 2021 | Emerging role of AMPA receptor subunit GluA1 in synaptic plasticity: Implications for Alzheimer's disease. | 22 |
| 33404979 | 2021 | AMPAr GluA1 Phosphorylation at Serine 845 in Limbic System Is Associated with Cardiac Autonomic Tone. | 1 |
| 34274350 | 2021 | GluA1-homomeric AMPA receptor in synaptic plasticity and neurological diseases. | 15 |
| 32767928 | 2021 | The Identification of Three Key Genes Related to Stemness in Thyroid Carcinoma through Comprehensive Analysis. | 2 |
| 33188547 | 2021 | Emerging role of AMPA receptor subunit GluA1 in synaptic plasticity: Implications for Alzheimer's disease. | 22 |
| 33404979 | 2021 | AMPAr GluA1 Phosphorylation at Serine 845 in Limbic System Is Associated with Cardiac Autonomic Tone. | 1 |
| 34274350 | 2021 | GluA1-homomeric AMPA receptor in synaptic plasticity and neurological diseases. | 15 |
| 29880883 | 2020 | Amygdala levels of the GluA1 subunit of glutamate receptors and its phosphorylation state at serine 845 in the anterior hippocampus are biomarkers of ictal fear but not anxiety. | 8 |
Citation
Dessen P
GRIA1 (glutamate ionotropic receptor AMPA type subunit 1)
Atlas Genet Cytogenet Oncol Haematol. 2008-12-01
Online version: http://atlasgeneticsoncology.org/gene/50538/gria1-(glutamate-ionotropic-receptor-ampa-type-subunit-1)
