Identity
HGNC
LOCATION
21q22.3
LOCUSID
ALIAS
EREG1,KNP3,LTRPC2,LTrpC-2,NUDT9H,NUDT9L1,TRPC7
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7226
MIM: 603749
HGNC: 12339
Ensembl: ENSG00000142185
Variants:
dbSNP: 7226
ClinVar: 7226
TCGA: ENSG00000142185
COSMIC: TRPM2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38242853 | 2024 | Identification of Ligands for Ion Channels: TRPM2. | 0 |
| 38242853 | 2024 | Identification of Ligands for Ion Channels: TRPM2. | 0 |
| 36619219 | 2023 | TRPM2 facilitates tumor progression of clear cell renal cell carcinoma by relieving Endoplasmic Reticulum Stress. | 2 |
| 37337283 | 2023 | TRPM2-mediated Ca(2+) signaling as a potential therapeutic target in cancer treatment: an updated review of its role in survival and proliferation of cancer cells. | 3 |
| 37541115 | 2023 | Knockdown of TRPM2 promotes osteogenic differentiation of human periodontal ligament stem cells by modulating NF-κB /NLRP3 pathway. | 0 |
| 37739206 | 2023 | TRPM2 as a conserved gatekeeper determines the vulnerability of DA neurons by mediating ROS sensing and calcium dyshomeostasis. | 0 |
| 37762313 | 2023 | Endoplasmic Reticulum Stress-Related Ten-Biomarker Risk Classifier for Survival Evaluation in Epithelial Ovarian Cancer and TRPM2: A Potential Therapeutic Target of Ovarian Cancer. | 1 |
| 37906101 | 2023 | TRPM2-L Participates in the Interleukin-6 Pathway to Enhance Tumor Growth in Prostate Cancer by Hypoxia-Inducible Factor-1α. | 1 |
| 36619219 | 2023 | TRPM2 facilitates tumor progression of clear cell renal cell carcinoma by relieving Endoplasmic Reticulum Stress. | 2 |
| 37337283 | 2023 | TRPM2-mediated Ca(2+) signaling as a potential therapeutic target in cancer treatment: an updated review of its role in survival and proliferation of cancer cells. | 3 |
| 37541115 | 2023 | Knockdown of TRPM2 promotes osteogenic differentiation of human periodontal ligament stem cells by modulating NF-κB /NLRP3 pathway. | 0 |
| 37739206 | 2023 | TRPM2 as a conserved gatekeeper determines the vulnerability of DA neurons by mediating ROS sensing and calcium dyshomeostasis. | 0 |
| 37762313 | 2023 | Endoplasmic Reticulum Stress-Related Ten-Biomarker Risk Classifier for Survival Evaluation in Epithelial Ovarian Cancer and TRPM2: A Potential Therapeutic Target of Ovarian Cancer. | 1 |
| 37906101 | 2023 | TRPM2-L Participates in the Interleukin-6 Pathway to Enhance Tumor Growth in Prostate Cancer by Hypoxia-Inducible Factor-1α. | 1 |
| 33689144 | 2022 | Response of TRPM2 Channel to Hypercapnic Acidosis and Role of Zn, Se, and GSH. | 0 |
Citation
Dessen P
TRPM2 (transient receptor potential cation channel subfamily M member 2)
Atlas Genet Cytogenet Oncol Haematol. 2008-12-01
Online version: http://atlasgeneticsoncology.org/gene/50540/trpm2-(transient-receptor-potential-cation-channel-subfamily-m-member-2)
