RBM39 (RNA binding motif protein 39)

2008-12-01  

Identity

HGNC
RBM39
LOCATION
20q11.22
LOCUSID
9584
ALIAS
CAPER,CAPERalpha,FSAP59,HCC1,RNPC2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9584
MIM: 604739
HGNC: 15923
Ensembl: ENSG00000131051

Variants:

dbSNP: 9584
ClinVar: 9584
TCGA: ENSG00000131051
COSMIC: RBM39

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000131051ENST00000253363Q14498
ENSG00000131051ENST00000253363A0A384NQ03
ENSG00000131051ENST00000338163G3XAC6
ENSG00000131051ENST00000361162Q14498
ENSG00000131051ENST00000374038Q5QP23
ENSG00000131051ENST00000397370A8MYG5
ENSG00000131051ENST00000403542F2Z3E6
ENSG00000131051ENST00000412738F2Z3E6
ENSG00000131051ENST00000416108F2Z3E6
ENSG00000131051ENST00000416529F8WF73
ENSG00000131051ENST00000425184H7BZG3
ENSG00000131051ENST00000426951H0Y6I9
ENSG00000131051ENST00000429968F2Z2Z5
ENSG00000131051ENST00000433027F8WF24
ENSG00000131051ENST00000434927Q5QP22
ENSG00000131051ENST00000444878F2Z3E6
ENSG00000131051ENST00000448303H0Y4X3
ENSG00000131051ENST00000449489F2Z3E6
ENSG00000131051ENST00000453310F2Z3E6
ENSG00000131051ENST00000455343F2Z3E6
ENSG00000131051ENST00000476806A0A087X122
ENSG00000131051ENST00000490484A0A0U1RQH7
ENSG00000131051ENST00000528062Q14498
ENSG00000131051ENST00000615771A0A0U1RQW2
ENSG00000131051ENST00000656873F2Z3E6

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
378523232024Regulatory role of RBM39 in acute myeloid leukemia: Mediation through the PI3K/AKT pathway.2
378523232024Regulatory role of RBM39 in acute myeloid leukemia: Mediation through the PI3K/AKT pathway.2
365356282023Insights on the biological functions and diverse regulation of RNA-binding protein 39 and their implication in human diseases.2
376668212023Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39.1
378048302023Arginine reprograms metabolism in liver cancer via RBM39.14
380650602023RBM39: A druggable metabolic sensor linking RNA splicing, transcriptional regulation, and metabolic reprogramming in cancer.0
365356282023Insights on the biological functions and diverse regulation of RNA-binding protein 39 and their implication in human diseases.2
376668212023Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39.1
378048302023Arginine reprograms metabolism in liver cancer via RBM39.14
380650602023RBM39: A druggable metabolic sensor linking RNA splicing, transcriptional regulation, and metabolic reprogramming in cancer.0
345201182022Identification of a small molecule splicing inhibitor targeting UHM domains.6
364773122022The transcription factor c-Jun inhibits RBM39 to reprogram pre-mRNA splicing during genotoxic stress.1
345201182022Identification of a small molecule splicing inhibitor targeting UHM domains.6
364773122022The transcription factor c-Jun inhibits RBM39 to reprogram pre-mRNA splicing during genotoxic stress.1
340777262021Inhibiting an RBM39/MLL1 epigenomic regulatory complex with dominant-negative peptides disrupts cancer cell transcription and proliferation.8

Citation

Dessen P

RBM39 (RNA binding motif protein 39)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50557/rbm39-(rna-binding-motif-protein-39)