Identity
HGNC
LOCATION
7q21.11
LOCUSID
ALIAS
Sema-Z2,coll-2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 223117
MIM: 609907
HGNC: 10726
Ensembl: ENSG00000153993
Variants:
dbSNP: 223117
ClinVar: 223117
TCGA: ENSG00000153993
COSMIC: SEMA3D
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000153993 | ENST00000284136 | O95025 |
| ENSG00000153993 | ENST00000444867 | C9JYT6 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Axon guidance | KEGG | ko04360 |
| Axon guidance | KEGG | hsa04360 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37219490 | 2023 | Tumor-derived semaphorin 3D promoting cancer cachexia via regulating hypothalamic pro-opiomelanocortin neurons. | 0 |
| 37219490 | 2023 | Tumor-derived semaphorin 3D promoting cancer cachexia via regulating hypothalamic pro-opiomelanocortin neurons. | 0 |
| 35190928 | 2022 | Semaphorin 3D inhibits proliferation and migration of papillary thyroid carcinoma by regulating MAPK/ERK signaling pathway. | 3 |
| 35190928 | 2022 | Semaphorin 3D inhibits proliferation and migration of papillary thyroid carcinoma by regulating MAPK/ERK signaling pathway. | 3 |
| 27876815 | 2017 | Variable expressivity and genetic heterogeneity involving DPT and SEMA3D genes in autosomal dominant familial Meniere's disease. | 28 |
| 28320475 | 2017 | Decreased expression of semaphorin 3D is associated with genesis and development in colorectal cancer. | 8 |
| 29074988 | 2017 | Promoter-level transcriptome in primary lesions of endometrial cancer identified biomarkers associated with lymph node metastasis. | 7 |
| 27876815 | 2017 | Variable expressivity and genetic heterogeneity involving DPT and SEMA3D genes in autosomal dominant familial Meniere's disease. | 28 |
| 28320475 | 2017 | Decreased expression of semaphorin 3D is associated with genesis and development in colorectal cancer. | 8 |
| 29074988 | 2017 | Promoter-level transcriptome in primary lesions of endometrial cancer identified biomarkers associated with lymph node metastasis. | 7 |
| 25839327 | 2015 | Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability. | 61 |
| 26073756 | 2015 | CTNNA3 and SEMA3D: Promising loci for asthma exacerbation identified through multiple genome-wide association studies. | 24 |
| 26286962 | 2015 | Class 3 semaphorins expression and association with innervation and angiogenesis within the degenerate human intervertebral disc. | 20 |
| 25839327 | 2015 | Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability. | 61 |
| 26073756 | 2015 | CTNNA3 and SEMA3D: Promising loci for asthma exacerbation identified through multiple genome-wide association studies. | 24 |
Citation
Dessen P
SEMA3D (semaphorin 3D)
Atlas Genet Cytogenet Oncol Haematol. 2008-12-01
Online version: http://atlasgeneticsoncology.org/gene/50589/sema3d-(semaphorin-3d)
