PDE8B (phosphodiesterase 8B)

2008-12-01  

Identity

HGNC
PDE8B
LOCATION
5q13.3
LOCUSID
8622
ALIAS
ADSD,PPNAD3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8622
MIM: 603390
HGNC: 8794
Ensembl: ENSG00000284762

Variants:

dbSNP: 8622
ClinVar: 8622
TCGA: ENSG00000284762
COSMIC: PDE8B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000284762ENST00000646262A0A2R8Y4E6

Pathways

PathwaySourceExternal ID
Purine metabolismKEGGko00230
Purine metabolismKEGGhsa00230
Morphine addictionKEGGhsa05032
Morphine addictionKEGGko05032
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (s) signalling eventsREACTOMER-HSA-418555

References

Pubmed IDYearTitleCitations
362777282022cAMP-specific phosphodiesterase 8A and 8B isoforms are differentially expressed in human testis and Leydig cell tumor.1
362777282022cAMP-specific phosphodiesterase 8A and 8B isoforms are differentially expressed in human testis and Leydig cell tumor.1
317262902019Clinical findings of autosomal-dominant striatal degeneration and PDE8B mutation screening in parkinsonism and related disorders.3
317262902019Clinical findings of autosomal-dominant striatal degeneration and PDE8B mutation screening in parkinsonism and related disorders.3
299091442018PDE8B mutation is not associated with Parkinson's disease in a Taiwanese population.1
299091442018PDE8B mutation is not associated with Parkinson's disease in a Taiwanese population.1
283825052017Association of established hypothyroidism-associated genetic variants with Hashimoto's thyroiditis.6
287276282017Replication confirms the association of loci in FOXE1, PDE8B, CAPZB and PDE10A with thyroid traits: a Genetics of Diabetes Audit and Research Tayside study (GoDARTS).5
283825052017Association of established hypothyroidism-associated genetic variants with Hashimoto's thyroiditis.6
287276282017Replication confirms the association of loci in FOXE1, PDE8B, CAPZB and PDE10A with thyroid traits: a Genetics of Diabetes Audit and Research Tayside study (GoDARTS).5
258228122015Genetic association study of phosphodiesterase 8B gene with subclinical hypothyroidism in pregnant women.1
267696072015A novel mutation of PDE8B Gene in a Japanese family with autosomal-dominant striatal degeneration.4
258228122015Genetic association study of phosphodiesterase 8B gene with subclinical hypothyroidism in pregnant women.1
267696072015A novel mutation of PDE8B Gene in a Japanese family with autosomal-dominant striatal degeneration.4
239415142014The phosphodiesterase 8B gene rs4704397 is associated with thyroid function, risk of myocardial infarction, and body height: the Tromsø study.2

Citation

Dessen P

PDE8B (phosphodiesterase 8B)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50598/pde8b-(phosphodiesterase-8b)