INHA (inhibin subunit alpha)

2003-02-01 Affiliation

Identity

HGNC

INHA

LOCATION

2q35

LOCUSID

3623

ALIAS

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 3623
MIM: 147380
HGNC: 6065
Ensembl: ENSG00000123999

Variants:

dbSNP: 3623
ClinVar: 3623
TCGA: ENSG00000123999
COSMIC: INHA

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000123999	ENST00000243786	P05111

Expression (GTEx)

100

150

200

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Metabolism of proteins	REACTOME	R-HSA-392499
Peptide hormone metabolism	REACTOME	R-HSA-2980736
Peptide hormone biosynthesis	REACTOME	R-HSA-209952
Glycoprotein hormones	REACTOME	R-HSA-209822

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
35235537	2022	Homozygosity for a novel INHA mutation in two male siblings with hypospadias, primary hypogonadism, and high-normal testicular volume.	2
35853432	2022	Altered Endometrial Expression of α-Inhibin Subunit and Its Co-Receptor Betaglycan in Infertile Women with Endometriosis.	2
35909548	2022	Testicular Sertoli Cell Hormones in Differences in Sex Development.	5
35235537	2022	Homozygosity for a novel INHA mutation in two male siblings with hypospadias, primary hypogonadism, and high-normal testicular volume.	2
35853432	2022	Altered Endometrial Expression of α-Inhibin Subunit and Its Co-Receptor Betaglycan in Infertile Women with Endometriosis.	2
35909548	2022	Testicular Sertoli Cell Hormones in Differences in Sex Development.	5
30340444	2020	Variations in the inhibin gene in Kashmiri women with primary ovarian insufficiency.	1
31982478	2020	ALK4-SMAD3/4 mediates the effects of activin A on the upregulation of PAI-1 in human granulosa lutein cells.	3
32569368	2020	Engineering the Ovarian Hormones Inhibin A and Inhibin B to Enhance Synthesis and Activity.	5
32593229	2020	Association of polymorphism c.-124G>A and c.-16 C>T in the promoter region of human INHA gene with altered sperm parameters; A pilot study.	4
32613604	2020	An exome-wide exploration of cases of primary ovarian insufficiency uncovers novel sequence variants and candidate genes.	7
32990126	2020	PAPP-A2 and Inhibin A as Novel Predictors for Pregnancy Complications in Women With Suspected or Confirmed Preeclampsia.	9
30340444	2020	Variations in the inhibin gene in Kashmiri women with primary ovarian insufficiency.	1
31982478	2020	ALK4-SMAD3/4 mediates the effects of activin A on the upregulation of PAI-1 in human granulosa lutein cells.	3
32569368	2020	Engineering the Ovarian Hormones Inhibin A and Inhibin B to Enhance Synthesis and Activity.	5

Citation

Dessen P

INHA (inhibin subunit alpha)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/506/inha-(inhibin-subunit-alpha)