ONECUT2 (one cut homeobox 2)

2008-12-01  

Identity

HGNC
LOCATION
18q21.31
LOCUSID
ALIAS
OC-2,OC2

Other Information

Locus ID:

NCBI: 9480
MIM: 604894
HGNC: 8139
Ensembl: ENSG00000119547

Variants:

dbSNP: 9480
ClinVar: 9480
TCGA: ENSG00000119547
COSMIC: ONECUT2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000119547ENST00000491143O95948

Expression (GTEx)

0
1
2
3
4
5

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
361780802022LncRNA TM1-3P Regulates Proliferation, Apoptosis and Inflammation of Fibroblasts in Osteoarthritis through miR-144-3p/ONECUT2 Axis.4
365083882022MicroRNA-1298-3p induces tumor-suppressive effects in human cervical cancer cells via post-transcriptional suppression of ONECUT2.2
361780802022LncRNA TM1-3P Regulates Proliferation, Apoptosis and Inflammation of Fibroblasts in Osteoarthritis through miR-144-3p/ONECUT2 Axis.4
365083882022MicroRNA-1298-3p induces tumor-suppressive effects in human cervical cancer cells via post-transcriptional suppression of ONECUT2.2
343658392021ONECUT2 which is targeted by hsa-miR-15a-5p enhances stemness maintenance of gastric cancer stem cells.4
343658392021ONECUT2 which is targeted by hsa-miR-15a-5p enhances stemness maintenance of gastric cancer stem cells.4
321298802020ONECUT2 upregulation is associated with CpG hypomethylation at promoter-proximal DNA in gastric cancer and triggers ACSL5.12
330157792020Up-regulated ONECUT2 and down-regulated SST promote gastric cell migration, invasion, epithelial-mesenchymal transition and tumor growth in gastric cancer.10
321298802020ONECUT2 upregulation is associated with CpG hypomethylation at promoter-proximal DNA in gastric cancer and triggers ACSL5.12
330157792020Up-regulated ONECUT2 and down-regulated SST promote gastric cell migration, invasion, epithelial-mesenchymal transition and tumor growth in gastric cancer.10
306555352019ONECUT2 is a driver of neuroendocrine prostate cancer.117
310495882019ONECUT transcription factors induce neuronal characteristics and remodel chromatin accessibility.27
311182002019Chemotherapy-Induced Extracellular Vesicle miRNAs Promote Breast Cancer Stemness by Targeting ONECUT2.92
318826552019ONECUT2 overexpression promotes RAS-driven lung adenocarcinoma progression.18
306555352019ONECUT2 is a driver of neuroendocrine prostate cancer.117

Citation

Dessen P

ONECUT2 (one cut homeobox 2)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50603/onecut2-(one-cut-homeobox-2)