HBA1 (hemoglobin subunit alpha 1)

2008-12-01

Identity

HGNC

HBA1

LOCATION

16p13.3

LOCUSID

3039

ALIAS

ECYT7,HBA-T3,HBH,METHBA

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 3039
MIM: 141800
HGNC: 4823
Ensembl: ENSG00000206172

Variants:

dbSNP: 3039
ClinVar: 3039
TCGA: ENSG00000206172
COSMIC: HBA1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000206172	ENST00000320868	P69905
ENSG00000206172	ENST00000320868	D1MGQ2
ENSG00000206172	ENST00000397797	G3V1N2

Expression (GTEx)

5000

10000

15000

20000

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
African trypanosomiasis	KEGG	ko05143
African trypanosomiasis	KEGG	hsa05143
Binding and Uptake of Ligands by Scavenger Receptors	REACTOME	R-HSA-2173782
Erythrocytes take up carbon dioxide and release oxygen	REACTOME	R-HSA-1237044
Erythrocytes take up oxygen and release carbon dioxide	REACTOME	R-HSA-1247673
Malaria	KEGG	ko05144
Malaria	KEGG	hsa05144
Metabolism	REACTOME	R-HSA-1430728
O2/CO2 exchange in erythrocytes	REACTOME	R-HSA-1480926
Scavenging of heme from plasma	REACTOME	R-HSA-2168880

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Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
34850006	2022	Continuous Glucose Monitoring and HbA1c in Cystic Fibrosis: Clinical Correlations and Implications for CFRD Diagnosis.	12
34988782	2022	Relationship between hemoglobin A1C and characteristics of plaque vulnerability in stable coronary disease: an optical coherence tomography study.	3
35052472	2022	Importance of Sequencing HBA1, HBA2 and HBB Genes to Confirm the Diagnosis of High Oxygen Affinity Hemoglobin.	1
35253121	2022	Differences in Hemoglobin A1c during Pregnancy between Non-Hispanic Black versus White Women with Prepregnancy Diabetes.	4
35859509	2022	Dental caries and their relation to hba1c in adults with type 2 diabetes mellitus.	0
36057557	2022	HbA1c at term delivery and adverse pregnancy outcome.	4
36117408	2022	Decreased expression of HBA1 and HBB genes in acute myeloid leukemia patients and their inhibitory effects on growth of K562 cells.	3
36655240	2023	[Value of glycosylated hemoglobin A1c and apolipoprotein A-1 ratio on predicting outcome of patients with acute coronary syndrome].	0
36655240	2023	[Value of glycosylated hemoglobin A1c and apolipoprotein A-1 ratio on predicting outcome of patients with acute coronary syndrome].	0
36674274	2023	Glutathione S-Transferase P1 Genetic Variant's Influence on the HbA1c Level in Type Two Diabetic Patients.	0

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Citation

Dessen P

HBA1 (hemoglobin subunit alpha 1)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50605